The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

Recent years have seen the emergence of tissue engineering strategies as a means to
overcome some of the limits of conventional medical treatment. A biomaterial with tailored …

Human dental pulp stem cells (hDPSCs) are easily obtained multipotent cells, however, their
potential value in regenerative medicine is hindered by the phenotypic and functional …

Aim The premixed bioceramic sealer iRoot SP that is widely used clinically has been
reported to kill bacterial biofilms and promote osteogenic differentiation of human stem cells …

Aim To establish and fully characterize a new cell line from human stem cells of the apical
papilla (SCAPs) through immortalization with an SV40 large T antigen. Methodology Human …

Tissue engineering strategies aim at characterizing and at optimizing the cellular component
that is combined with biomaterials, for improved tissue regeneration. Here, we present the …

Tooth root development involves intricate spatiotemporal cellular dynamics and molecular
regulation. The initiation of Hertwig's epithelial root sheath (HERS) induces odontoblast …

Despite the popularity of mesenchymal stem cells (MSCs), many fundamental aspects of
their physiology still have not been understood. The information accumulated to date argues …

Spinal cord injury (SCI), a prevalent and disabling neurological condition, prompts a
growing interest in stem cell therapy as a promising avenue for treatment. Dental-derived …

The homeostasis of adult tissues, such as skin, hair, blood, and bone, requires continuous
generation of differentiated progeny of stem cells. The rodent incisor undergoes constant …