The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …

In this short review, we give an overview of microtubule nucleation within cells. It is nearly 30
years since the discovery of γ-tubulin, a member of the tubulin superfamily essential for …

The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …

Regulation of the γ-tubulin ring complex (γTuRC) through targeting and activation restricts
nucleation of microtubules to microtubule-organizing centers (MTOCs), aiding in the …

Centrosomes are a functionally conserved feature of eukaryotic cells that play an important
role in cell division. The conserved γ-tubulin complex organizes spindle and astral …

Microtubules are major constituents of the cytoskeleton in all eukaryotic cells. They are
essential for chromosome segregation during cell division, for directional intracellular …

Non-centrosomal microtubule organizing centers (MTOCs) direct microtubule (MT)
organization to exert diverse cell-type-specific functions. In Drosophila spermatids, the giant …

MOZART1/Mzt1 is required for the localization of γ-tubulin complexes to microtubule (MT)–
organizing centers from yeast to human cells. Nevertheless, the molecular function of …

Microtubule-organizing centers (MTOCs), known as centrosomes in animals and spindle
pole bodies (SPBs) in fungi, are important for the faithful distribution of chromosomes …