Despite expressing many key risk genes, the role of microglia in late-onset Alzheimer's
disease pathophysiology is somewhat ambiguous, with various phenotypes reported to be …

Microglia are specialized brain-resident macrophages that arise from primitive macrophages
colonizing the embryonic brain. Microglia contribute to multiple aspects of brain …

Microglia belong to tissue-resident macrophages of the central nervous system (CNS),
representing the primary innate immune cells. This cell type constitutes~ 7% of non …

Microglial activation during neuroinflammation is crucial for coordinating the immune
response against neuronal tissue, and the initial response of microglia determines the …

Neuroinflammation is a hallmark of many neurological diseases, including traumatic brain
injury (TBI), which is usually characterized by two pathological hallmarks: activation of …

Microglia play an important role in the pathology of various central nervous system
disorders, including multiple sclerosis (MS). While different methods exist to evaluate the …

Sleep is a natural physiological state, tightly regulated through several neuroanatomical and
neurochemical systems, which is essential to maintain physical and mental health. Recent …

As the resident parenchymal myeloid population in the central nervous system (CNS),
microglia are strategically positioned to respond to neurotropic virus invasion and have …

Microglia and bone marrow‐derived monocytes are key elements of central nervous system
(CNS) inflammation, both capable of enhancing and dampening immune‐mediated …

The infection of the central nervous system (CNS) with neurotropic viruses induces
neuroinflammation and is associated with the development of neuroinflammatory and …