Indole–a promising pharmacophore in recent antiviral drug discovery

A Dorababu - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
The bicyclic molecule indole has been in the limelight because of its numerous
pharmacological potencies. It is used as an excellent scaffold in drug discovery of medicinal …

Development of azaindole-based frameworks as potential antiviral agents and their future perspectives

Urvashi, JB Senthil Kumar, P Das… - Journal of Medicinal …, 2022 - ACS Publications
The azaindole (AI) framework continues to play a significant role in the design of new
antiviral agents. Modulating the position and isosteric replacement of the nitrogen atom of AI …

Synthesis of C3, C6-Diaryl 7-Azaindoles via One-Pot Suzuki–Miyaura Cross-Coupling Reaction and Evaluation of Their HIV-1 Integrase Inhibitory Activity

S Cardoza, P Yadav, A Ajmani, P Das, V Tandon - ACS omega, 2023 - ACS Publications
There is a continuing demand of new inhibitors of HIV-1 Integrase (HIV-1 IN) due to
mutations of HIV-1. This study aims to develop the synthesis of 3, 6-diaryl 7-azaindoles and …