N6-methyladenosine modification: A potential regulatory mechanism in spinal cord injury

D Liu, B Fan, J Li, T Sun, J Ma, X Zhou… - Frontiers in Cellular …, 2022 - frontiersin.org
N6-methyladenosine (m6A), an essential post-transcriptional modification in eukaryotes, is
closely related to the development of pathological processes in neurological diseases …

The role and regulatory mechanism of m6A methylation in the nervous system

L Jiang, X Li, S Wang, Z Yuan, J Cheng - Frontiers in Genetics, 2022 - frontiersin.org
N6-methyladenosine (m6A) modification regulates RNA translation, splicing, transport,
localization, and stability at the post-transcriptional level. The m6A modification has been …

Emerging roles for DNA 6mA and RNA m6A methylation in mammalian genome

L Xie, X Zhang, J Xie, Y Xu, XJ Li, L Lin - International Journal of …, 2023 - mdpi.com
Epigenetic methylation has been shown to play an important role in transcriptional
regulation and disease pathogenesis. Recent advancements in detection techniques have …

Unraveling the molecular complexity: Wtap/Ythdf1 and Lcn2 in novel traumatic brain injury secondary injury mechanisms

C Ma, C Gou, S Sun, J Wang, X Wei, F Xing… - Cell Biology and …, 2024 - Springer
The primary aim of this research was to explore the functions of Wtap and Ythdf1 in
regulating neuronal Lipocalin-2 (Lcn2) through m6A modification in traumatic brain injury …

WTAP regulates stem cells via TRAF6 to maintain planarian homeostasis and regeneration

H Zhen, M Huang, M Zheng, L Gao, Z Guo… - International Journal of …, 2023 - Elsevier
WTAP, a highly conserved Wilms' tumor 1 interacting protein, is involved in a variety of
biological processes. However, functional studies of WTAP in planarians have not been …

The complex roles of m6A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative …

Y Li, J Xue, Y Ma, K Ye, X Zhao, F Ge… - Neural Regeneration …, 2025 - journals.lww.com
Abstract N6-methyladenosine (m 6 A), the most prevalent and conserved RNA modification
in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA …

[HTML][HTML] JGG in 2022: challenges, opportunities, and prospects

X Guo, XF Song, J Zuo - Journal of Genetics and Genomics, 2023 - ncbi.nlm.nih.gov
(JGG) has seen a variety of challenges as well as opportunities. At the difficult time of the
COVID-19 pandemic, we have gone through unforeseen difficulties, including the …

Effects of the Co-Administration of Thyme and Tramadol on The Postnatal Development of Purkinje Neurons of The Albino Rat

MEB Mohamed, HA Mohamed, GR Ghait… - … Academic Journal of …, 2022 - journals.ekb.eg
Background: Tramadol is a painkiller that works by acting on the central nervous system.
Even though tramadol is regarded to have minimal misuse and dependence potential, it is …

Research progress of m6A modification in spinal cord injury recovery.

Z Dongxu, Z Xinhua, J Huanying… - Journal of Practical …, 2023 - search.ebscohost.com
Spinal cord injury (SCI) is a serious disease of the central nervous system (CNS), which
often leads to motor dysfunction and is associated with a variety of serious complications …

The role of RNA demethylase FTO in differentiation, regulation of energy metabolism and sensitivity to streptozotocin of neuronal and glial cell models

Z Čočková - 2023 - dspace.cuni.cz
Fat mass and obesity associated (FTO) demethylase is responsible for erasure of the most
abundant epitranscriptomic mark in eukaryotic mRNA, the N6-methyladenosine (m6A) …