[HTML][HTML] Resveratrol: A Multifaceted Guardian against Anxiety and Stress Disorders—An Overview of Experimental Evidence

VE Tseilikman, OB Tseilikman, ON Yegorov… - Nutrients, 2024 - mdpi.com
The medicinal properties of resveratrol have garnered increasing attention from researchers.
Extensive data have been accumulated on its use in treating cardiovascular diseases …

[HTML][HTML] Flavonoids and Their Role in Preventing the Development and Progression of MAFLD by Modifying the Microbiota

A Sokal-Dembowska, S Jarmakiewicz-Czaja… - International Journal of …, 2024 - mdpi.com
With the increasing prevalence and serious health consequences of metabolic-associated
fatty liver disease (MAFLD), early diagnosis and intervention are key to effective treatment …

Resveratrol attenuates non-steroidal anti-inflammatory drug-induced intestinal injury in rats in a high-altitude hypoxic environment by modulating the TLR4/NFκB/IκB …

S Xue, W Shi, T Shi, A Tuerxuntayi, P Abulaiti, Z Liu… - Plos one, 2024 - journals.plos.org
Introduction Non-steroidal anti-inflammatory drugs (NSAIDs) are currently the most widely
used anti-inflammatory medications, but their long-term use can cause damage to the …

[HTML][HTML] Unraveling the Liver–Brain Axis: Resveratrol's Modulation of Key Enzymes in Stress-Related Anxiety

VE Tseilikman, OB Tseilikman, VA Shevyrin… - Biomedicines, 2024 - mdpi.com
Stress-related anxiety disorders and anxiety-like behavior in post-traumatic stress disorder
(PTSD) are associated with altered neurocircuitry pathways, neurotransmitter systems, and …

Heteroaryl Group Containing Trisubstituted Alkenes: Synthesis and Anti‐tumor Activity

J Li, A Gu, MY Li - Chemistry & Biodiversity, 2024 - Wiley Online Library
Pancreatobililary cancers are fatal solid tumors that pose a significant threat to human life. It
is imperative to investigate novel small molecule active compounds for controlling these …

Perspective on the Coevolutionary Role of Host and Gut Microbiota in Polyphenol Health Effects: Metabotypes and Precision Health

JC Espín, MP Jarrín‐Orozco… - Molecular Nutrition & …, 2024 - Wiley Online Library
Abstract “Personalized nutrition” aims to establish nutritional strategies to improve health
outcomes for non‐responders. However, it is utopian since most people share similar …

[HTML][HTML] Advancements in Autophagy Modulation for the Management of Oral Disease: A Focus on Drug Targets and Therapeutics

MA Rahman, MH Shaikh, RD Gupta, N Siddika… - Biomedicines, 2024 - mdpi.com
Autophagy is an intrinsic breakdown system that recycles organelles and macromolecules,
which influences metabolic pathways, differentiation, and thereby cell survival. Oral health is …

[HTML][HTML] Investigating the Molecular Mechanisms of Resveratrol in Treating Cardiometabolic Multimorbidity: A Network Pharmacology and Bioinformatics Approach …

W Gong, P Sun, X Li, X Wang, X Zhang, H Cui, J Yang - Nutrients, 2024 - mdpi.com
Background: Resveratrol is a potent phytochemical known for its potential in treating
cardiometabolic multimorbidity. However, its underlying mechanisms remain unclear. Our …

[HTML][HTML] Harnessing the Anti-Inflammatory Properties of Polyphenols in the Treatment of Inflammatory Bowel Disease

DL Boaru, O Fraile-Martinez… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) encompasses a spectrum of chronic inflammatory
conditions affecting the gastrointestinal tract, notably ulcerative colitis (UC) and Crohn's …

[HTML][HTML] Role of Oxidative Stress in Blood–Brain Barrier Disruption and Neurodegenerative Diseases

S Kim, UJ Jung, SR Kim - Antioxidants, 2024 - pmc.ncbi.nlm.nih.gov
Upregulation of reactive oxygen species (ROS) levels is a principal feature observed in the
brains of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's …