Mast cells are well accepted as important sentinel cells for host defence against selected
pathogens. Their location at mucosal surfaces and ability to mobilize multiple aspects of …

Mast cells have mainly been studied in the setting of allergic disease, but the importance of
mast cells for host defence against several pathogens has now been well established. The …

A major obstacle in human immunodeficiency virus type 1 (HIV-1) eradication is the ability of
the virus to remain latent in a subpopulation of the cells it infects. Latently infected cells can …

Mast cells (MCs) are active participants in blood coagulation and innate and acquired
immunity. This review focuses on the development of mouse and human MCs, as well as the …

Mast cells are highly effective sentinel cells, found close to blood vessels and especially
common sites of potential infection, such as the skin, airways and gastrointestinal tract. Mast …

Chemokines, representing a large superfamily of 8-to 15-kd proteins, were originally
discovered through their ability to recruit various cell types into sites of inflammation. It is …

Although it has been shown that mast cell-deficient mice have diminished innate immune
responses against bacteria, the most important immunoprotective factors secreted from …

Mast cells (MCs) are cells of hematopoietic origin that normally reside in mucosal tissues,
often near epithelial cells, glands, smooth muscle cells, and nerves. Best known for their …

Human mast cells are found in skin and mucosal surfaces and next to blood vessels. They
play a sentinel cell role in immunity, recognizing invading pathogens and producing …

There is a growing interest in the role of chemokines and their receptors in the determination
of mast cell tissue localization and how chemokines regulate mast cell function. At least nine …