Background Ubiquicidin is a peptide fragment with selective binding to negatively charged
bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it …

Infections of the bones and joints, if misdiagnosed, may result in serious morbidity and even
mortality. A prompt diagnosis followed by appropriate management may reduce the …

Real-time localization and microbial activity information of indigenous gut microbiota over an
extended period of time remains a challenge with existing visualizing methods. Here, we …

Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …

The in situ immediate detection of the presence of bacteria in the distal human lung is of
significant clinical utility. Herein we describe the development and optimization of a bacterial …

Background Bacterial infections are still a major global healthcare problem. To combat the
increasing antimicrobial resistance, early diagnosis of bacterial infections—including the …

Metabolic imaging has come to occupy a prominent place in the diagnosis and management
of microbial infection. Molecular probes available for infection imaging have undergone a …

Despite significant advances in the understanding of microorganisms and an increased
availability of antimicrobial therapy, infection remains a major cause of morbidity and …

In trauma and orthopedic surgery, infection of implants has a major impact on the outcome
for patients. Infections may develop either during the initial implantation or during the lifetime …

Rapid in situ detection of pathogens coupled with high resolution imaging in the distal
human lung has the potential to provide new insights and diagnostic utility in patients in …