Metagenomics and future perspectives in virus discovery
Monitoring the emergence and re-emergence of viral diseases with the goal of containing
the spread of viral agents requires both adequate preparedness and quick response …
the spread of viral agents requires both adequate preparedness and quick response …
Encapsulins
TW Giessen - Annual review of biochemistry, 2022 - annualreviews.org
Subcellular compartmentalization is a defining feature of all cells. In prokaryotes,
compartmentalization is generally achieved via protein-based strategies. The two main …
compartmentalization is generally achieved via protein-based strategies. The two main …
Multiple origins of viral capsid proteins from cellular ancestors
M Krupovic, EV Koonin - Proceedings of the National …, 2017 - National Acad Sciences
Viruses are the most abundant biological entities on earth and show remarkable diversity of
genome sequences, replication and expression strategies, and virion structures …
genome sequences, replication and expression strategies, and virion structures …
A virus capsid‐like nanocompartment that stores iron and protects bacteria from oxidative stress
Living cells compartmentalize materials and enzymatic reactions to increase metabolic
efficiency. While eukaryotes use membrane‐bound organelles, bacteria and archaea rely …
efficiency. While eukaryotes use membrane‐bound organelles, bacteria and archaea rely …
Advances in encapsulin nanocompartment biology and engineering
JA Jones, TW Giessen - Biotechnology and bioengineering, 2021 - Wiley Online Library
Compartmentalization is an essential feature of all cells. It allows cells to segregate and
coordinate physiological functions in a controlled and ordered manner. Different …
coordinate physiological functions in a controlled and ordered manner. Different …
Large-scale computational discovery and analysis of virus-derived microbial nanocompartments
MP Andreas, TW Giessen - Nature Communications, 2021 - nature.com
Encapsulins are a class of microbial protein compartments defined by the viral HK97-fold of
their capsid protein, self-assembly into icosahedral shells, and dedicated cargo loading …
their capsid protein, self-assembly into icosahedral shells, and dedicated cargo loading …
Cryo-EM structure of Mycobacterium smegmatis DyP-loaded encapsulin
Y Tang, A Mu, Y Zhang, S Zhou… - Proceedings of the …, 2021 - National Acad Sciences
Encapsulins containing dye-decolorizing peroxidase (DyP)-type peroxidases are ubiquitous
among prokaryotes, protecting cells against oxidative stress. However, little is known about …
among prokaryotes, protecting cells against oxidative stress. However, little is known about …
Encapsulins—Bacterial protein nanocompartments: Structure, properties, and application
AN Gabashvili, NS Chmelyuk, MV Efremova… - Biomolecules, 2020 - mdpi.com
Recently, a new class of prokaryotic compartments, collectively called encapsulins or protein
nanocompartments, has been discovered. The shell proteins of these structures self …
nanocompartments, has been discovered. The shell proteins of these structures self …
Encapsulins: molecular biology of the shell
RJ Nichols, C Cassidy-Amstutz… - Critical Reviews in …, 2017 - Taylor & Francis
Compartmentalization is both a fundamental principle of cellular organization and an
emerging theme in prokaryotic biology. Work in the past few decades has shown that protein …
emerging theme in prokaryotic biology. Work in the past few decades has shown that protein …
Encapsulins: microbial nanocompartments with applications in biomedicine, nanobiotechnology and materials science
TW Giessen - Current opinion in chemical biology, 2016 - Elsevier
Highlights•Encapsulins are a new class of microbial protein nanocompartments with
diameters of 24 or 32 nm.•They naturally encapsulate a variety of cargo proteins related to …
diameters of 24 or 32 nm.•They naturally encapsulate a variety of cargo proteins related to …