Epigenome-wide association studies: current knowledge, strategies and recommendations
The aetiology and pathophysiology of complex diseases are driven by the interaction
between genetic and environmental factors. The variability in risk and outcomes in these …
between genetic and environmental factors. The variability in risk and outcomes in these …
Management of functional neurological disorder
GS Gilmour, G Nielsen, T Teodoro, M Yogarajah… - Journal of …, 2020 - Springer
Functional neurological disorder (FND) is a common cause of persistent and disabling
neurological symptoms. These symptoms are varied and include abnormal control of …
neurological symptoms. These symptoms are varied and include abnormal control of …
Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes
A FC Lopes - Clinical Epigenetics, 2020 - Springer
Mitochondria are controlled by the coordination of two genomes: the mitochondrial and the
nuclear DNA. As such, variations in nuclear gene expression as a consequence of …
nuclear DNA. As such, variations in nuclear gene expression as a consequence of …
Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental …
Background Obesity is a negative chronic metabolic health condition that represents an
additional risk for the development of multiple pathologies. Epidemiological studies have …
additional risk for the development of multiple pathologies. Epidemiological studies have …
DNA Methylation Dynamics in Atlantic Salmon (Salmo salar) Challenged With High Temperature and Moderate Hypoxia
The marine environment is predicted to become warmer and more hypoxic, and these
conditions may become a challenge for marine fish species. Phenotypically plastic …
conditions may become a challenge for marine fish species. Phenotypically plastic …
A unified model of the biology of peripartum depression
Peripartum depression (PPD) is a prevalent and debilitating disorder that adversely affects
the development of mothers and infants. Recently, there has been a plea for increased …
the development of mothers and infants. Recently, there has been a plea for increased …
[HTML][HTML] Prenatal exposure to phthalates and peripheral blood and buccal epithelial DNA methylation in infants: an epigenome-wide association study
Background Prenatal exposure to phthalates has been associated with adverse health and
neurodevelopmental outcomes. DNA methylation (DNAm) alterations may be a mechanism …
neurodevelopmental outcomes. DNA methylation (DNAm) alterations may be a mechanism …
Childhood trauma and epigenetics: state of the science and future
Abstract Purpose of Review There is a great deal of interest regarding the biological
embedding of childhood trauma and social exposures through epigenetic mechanisms …
embedding of childhood trauma and social exposures through epigenetic mechanisms …
[HTML][HTML] Effect of prenatal bisphenol A exposure on early childhood body mass index through epigenetic influence on the insulin-like growth factor 2 receptor (IGF2R) …
Objectives Epigenetic mechanisms have been suggested to play a role in the link between
in utero exposure to bisphenol A (BPA) and pediatric obesity; however, there is little …
in utero exposure to bisphenol A (BPA) and pediatric obesity; however, there is little …
[HTML][HTML] Association of phthalate exposure with autistic traits in children
Background Phthalates are synthetic chemicals with endocrine-disrupting properties. They
are reportedly associated with various neurotoxic outcomes. Studies on exposure to …
are reportedly associated with various neurotoxic outcomes. Studies on exposure to …