Multiple myeloma: diagnosis and treatment

SV Rajkumar, S Kumar - Mayo Clinic Proceedings, 2016 - Elsevier
The diagnosis and treatment of multiple myeloma has changed dramatically in the past
decade. The disease definition has been updated to include highly specific biomarkers in …

Monoclonal gammopathy of renal significance: when MGUS is no longer undetermined or insignificant

N Leung, F Bridoux, CA Hutchison… - Blood, The Journal …, 2012 - ashpublications.org
Multiple myeloma is the most frequent monoclonal gammopathy to involve the kidney;
however, a growing number of kidney diseases associated with other monoclonal …

Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

P Moreau, J San Miguel, P Sonneveld… - Annals of …, 2017 - annalsofoncology.org
Multiple myeloma (MM) accounts for 1% of all cancers and $10% of all haematological
malignancies. The incidence in Europe is 4.5–6.0/100 000/year with a median age at …

Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline

J Mikhael, N Ismaila, MC Cheung, C Costello… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE To provide evidence-based recommendations on the treatment of multiple
myeloma to practicing physicians and others. METHODS ASCO and Cancer Care Ontario …

International Myeloma Working Group recommendations for the diagnosis and management of myeloma-related renal impairment

MA Dimopoulos, P Sonneveld, N Leung… - Journal of Clinical …, 2016 - ascopubs.org
Purpose The aim of the International Myeloma Working Group was to develop practical
recommendations for the diagnosis and management of multiple myeloma–related renal …

[HTML][HTML] European Myeloma Network guidelines for the management of multiple myeloma-related complications

E Terpos, M Kleber, M Engelhardt, S Zweegman… - …, 2015 - ncbi.nlm.nih.gov
Abstract The European Myeloma Network provides recommendations for the management
of the most common complications of multiple myeloma. Whole body low-dose computed …

[HTML][HTML] European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European …

D Averbuch, C Orasch, C Cordonnier… - …, 2013 - ncbi.nlm.nih.gov
Owing to increasing resistance and the limited arsenal of new antibiotics, especially against
Gram-negative pathogens, carefully designed antibiotic regimens are obligatory for febrile …

Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/GMMG-HD4 trial

P Sonneveld, IGH Schmidt-Wolf… - Journal of clinical …, 2012 - ascopubs.org
Purpose We investigated whether bortezomib during induction and maintenance improves
survival in newly diagnosed multiple myeloma (MM). Patients and Methods In all, 827 …

Management of multiple myeloma-related renal impairment: recommendations from the International Myeloma Working Group

MA Dimopoulos, G Merlini, F Bridoux, N Leung… - The Lancet …, 2023 - thelancet.com
Summary Here, the International Myeloma Working Group (IMWG) updates its clinical
practice recommendations for the management of multiple myeloma-related renal …

Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation …

Q Ping Dou, JA Zonder - Current cancer drug targets, 2014 - ingentaconnect.com
Over the past ten years, proteasome inhibition has emerged as an effective therapeutic
strategy for treating multiple myeloma (MM) and some lymphomas. In 2003, Bortezomib …