Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Clinical practice guideline for screening and management of high blood pressure in children and adolescents

JT Flynn, DC Kaelber, CM Baker-Smith, D Blowey… - …, 2017 - publications.aap.org
These pediatric hypertension guidelines are an update to the 2004 “Fourth Report on the
Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents.” …

The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline

JW Funder, RM Carey, F Mantero… - The Journal of …, 2016 - academic.oup.com
Objective: To develop clinical practice guidelines for the management of patients with
primary aldosteronism. Participants: The Task Force included a chair, selected by the …

Hypertension: renin–angiotensin–aldosterone system alterations

L Te Riet, JHM van Esch, AJM Roks… - Circulation …, 2015 - Am Heart Assoc
Blockers of the renin–angiotensin–aldosterone system (RAAS), that is, renin inhibitors,
angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists …

Diagnosis and treatment of primary aldosteronism: practical clinical perspectives

WF Young Jr - Journal of internal medicine, 2019 - Wiley Online Library
Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

The expanding spectrum of primary aldosteronism: implications for diagnosis, pathogenesis, and treatment

A Vaidya, P Mulatero, R Baudrand… - Endocrine …, 2018 - academic.oup.com
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Role of the renin-angiotensin-aldosterone system beyond blood pressure regulation: molecular and cellular mechanisms involved in end-organ damage during …

N Muñoz-Durango, CA Fuentes, AE Castillo… - International journal of …, 2016 - mdpi.com
Arterial hypertension is a common condition worldwide and an important predictor of several
complicated diseases. Arterial hypertension can be triggered by many factors, including …

An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism

GP Rossi, RJ Auchus, M Brown, JWM Lenders… - …, 2014 - Am Heart Assoc
Adrenal venous sampling is recommended by current guidelines to identify surgically
curable causes of hyperaldosteronism but remains markedly underused. Key factors …

Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism

UI Scholl, G Goh, G Stölting, RC De Oliveira, M Choi… - Nature …, 2013 - nature.com
Adrenal aldosterone-producing adenomas (APAs) constitutively produce the salt-retaining
hormone aldosterone and are a common cause of severe hypertension. Recurrent …

CLCN2 chloride channel mutations in familial hyperaldosteronism type II

UI Scholl, G Stölting, J Schewe, A Thiel, H Tan… - Nature …, 2018 - nature.com
Primary aldosteronism, a common cause of severe hypertension, features constitutive
production of the adrenal steroid aldosterone. We analyzed a multiplex family with familial …