Miniaturised nucleic acid analysis

PA Auroux, Y Koc, A DeMello, A Manz, PJR Day - Lab on a Chip, 2004 - pubs.rsc.org
The application of micro total analysis systems has grown exponentially over the past few
years, particularly diversifying in disciplines related to bioassays. The primary focus of this …

Solid supports for micro analytical systems

DS Peterson - Lab on a Chip, 2005 - pubs.rsc.org
The development of micro analytical systems requires that fluids are able to interact with the
surface of the microfluidic chip in order to perform analysis such as chromatography, solid …

A fully automated immunoassay from whole blood on a disc

BS Lee, JN Lee, JM Park, JG Lee, S Kim, YK Cho… - Lab on a Chip, 2009 - pubs.rsc.org
A portable, disc-based, and fully automated enzyme-linked immuno-sorbent assay (ELISA)
system is developed to test infectious diseases from whole blood. The innovative laser …

Focusbeads and chips: New recipes for analysis

E Verpoorte - Lab on a Chip, 2003 - pubs.rsc.org
View Article Online/Journal Homepage/Table of Contents for this issue interaction to a
specific point in the analysis system. In the case of dilute suspensions, separation of the …

Mobile magnetic particles as solid-supports for rapid surface-based bioanalysis in continuous flow

SA Peyman, A Iles, N Pamme - Lab on a Chip, 2009 - pubs.rsc.org
An extremely versatile microfluidic device is demonstrated in which multi-step (bio) chemical
procedures can be performed in continuous flow. The system operates by generating …

Simultaneous bioassays in a microfluidic channel on plugs of different magnetic particles

S Bronzeau, N Pamme - Analytica chimica acta, 2008 - Elsevier
Magnetic particles coated with specific biomolecules are often used as solid supports for
bioassays but conventional test tube based techniques are time consuming and labour …

[HTML][HTML] The emerging use of bioluminescence in medical research

S Sharifian, A Homaei, R Hemmati, RB Luwor… - Biomedicine & …, 2018 - Elsevier
Bioluminescence is the light produced by a living organism and is commonly emitted by sea
life with Ca 2+-regulated photoproteins being the most responsible for bioluminescence …

Nanomaterials and chip‐based nanostructures for capillary electrophoretic separations of DNA

YW Lin, MF Huang, HT Chang - Electrophoresis, 2005 - Wiley Online Library
Capillary electrophoresis (CE) and microchip capillary electrophoresis (MCE) using polymer
solutions are two of the most powerful techniques for the analysis of DNA. Problems, such as …

Pinched flow fractionation devices for detection of single nucleotide polymorphisms

AV Larsen, L Poulsen, H Birgens, M Dufva… - Lab on a Chip, 2008 - pubs.rsc.org
We demonstrate a new and flexible microfluidic based method for genotyping single
nucleotide polymorphisms (SNPs). The method relies on size separation of selectively …

On-chip immunoassay using electrostatic assembly of streptavidin-coated bead micropatterns

V Sivagnanam, B Song, C Vandevyver… - Analytical …, 2009 - ACS Publications
We propose an original concept for a sandwich immunoassay that is completely performed
on-chip using streptavidin-coated beads as substrate. The latter are electrostatically self …