Metabologenomics integrates metabolomics with other omics data types to comprehensively
study the genetic and environmental factors that influence metabolism. These multi-omics …

Toxicogenomics measures molecular features, such as transcripts, proteins, metabolites and
epigenomic modifications, to understand and predict the toxicological effects of …

Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

Proteins cooperate, regulate and bind each other to achieve their functions. Understanding
the complex network of their interactions is essential for a systems-level description of …

Background Sodium-glucose cotransporter 2 inhibitors (SGLT-2i) are glucose-lowering
agents used for the treatment of type 2 diabetes mellitus, which also improve heart failure …

This manuscript describes the development of a resource module that is part of a learning
platform named 'NIGMS Sandbox for Cloud-based Learning'(https://github …

The unraveling of the regulatory mechanisms that govern neuronal excitability is a major
challenge for neuroscientists worldwide. Neurotransmitters play a critical role in maintaining …

Abstract The Complex Portal (www. ebi. ac. uk/complexportal) is a manually curated
reference database for molecular complexes. It is a unifying web resource linking …

Cellular senescence is a cell fate driven by different types of stress, where damaged cells
exit from the cell cycle and, in many cases, develop an inflammatory senescence-associated …

In animal models, Nipbl deficiency phenocopies gene expression changes and birth defects
seen in Cornelia de Lange syndrome, the most common cause of which is Nipbl …