Cholestasis is characterized by impaired bile flow which results in inflammation, cirrhosis,
and ultimately liver failure. The current study is aimed to evaluate the anti-cholestatic effect …

Background: Being the main metabolic organ, liver stays in touch with toxicity of introduced
materials including, drugs. Protection is priceless to avoid complication of liver toxicity …

Аннотация Введение. Цикорий обыкновенный (Cichorium intybus L.) широко
используется в традиционной медицине различных стран при заболеваниях печени, а …

Introduction The present research describes the utilization of natural deep eutectic solvent in
combination with ultrasound for the extraction of milk thistle polyphenols. The extracts …

Valproic acid (VA) is a broad-spectrum anticonvulsant agent that acts through several
molecular mechanisms to control different types of seizures. The main concern of the drug is …

Background: Cirrhotic cardiomyopathy is a well-recognized cardiac dysfunction in cirrhotic
patients. Studies have confirmed the protective effects of silymarin in different types of …

Objectives: The most important toxicity of acetaminophen is hepatotoxicity. Farnesoid X-
activated receptors (FXR) are one of the nuclear receptor superfamily members which have …

Objective: Silibinin has exhibited antitumor activities. However, there are few reports about
the immunomodulatory properties of silibinin on T lymphocyte function in the tumor …

Objective (s): This study aimed to evaluate the relationship between Farnesoid-X-activated
receptors (FXR) as nuclear regulators of the antioxidant defense system as well as cardiac …

Abstract Introduction. Chicory (Cichorium intybus L.) is widely applied for liver disease
treatment by traditional medicine of different countries; as well, it is the object for …