Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics

C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

Allogeneic hematopoietic stem cell transplantation in the COVID-19 era

J Bordat, S Maury, M Leclerc - Frontiers in immunology, 2023 - frontiersin.org
Allogeneic hematopoietic stem-cell transplantation (allo-HSCT) recipients are especially
vulnerable to coronavirus disease 19 (COVID-19), because of their profound …

Fresh or frozen grafts for allogeneic stem cell transplantation: conceptual considerations and a survey on the practice during the COVID-19 pandemic from the EBMT …

N Worel, P Ljungman, ICM Verheggen… - Bone Marrow …, 2023 - nature.com
The COVID-19 pandemic has had a significant impact on medical practices, including the
delivery of allogeneic hematopoietic cell transplantation (HCT). In response, transplant …

Suitability of haematopoietic cell donors: updated consensus recommendations from the WBMT standing committee on donor issues

N Worel, M Aljurf, C Anthias, AS Buser… - The Lancet …, 2022 - thelancet.com
The contribution of related donors to the globally rising number of allogeneic haematopoietic
stem cell transplantations (HSCT) remains increasingly important, particularly because of …

[HTML][HTML] Lower incidence of chronic GVHD observed after transplantation with cryopreserved unrelated allogeneic stem cells

K Maurer, HT Kim, HM Garrity, D Liney, C Cutler… - Blood …, 2023 - ncbi.nlm.nih.gov
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) typically utilizes fresh donor
bone marrow (BM) or peripheral blood stem cells (PBSCs) because of concerns that …

Clinical impact of cryopreservation of allogeneic hematopoietic cell grafts during the onset of the COVID-19 pandemic

SM Devine, S Bo-Subait, M Kuxhausen… - Blood …, 2023 - ashpublications.org
At the onset of the COVID-19 pandemic, the National Marrow Donor Program mandated the
cryopreservation of hematopoietic cell grafts from volunteer unrelated donors because of …

Real-world experience of cryopreserved allogeneic hematopoietic grafts during the COVID-19 pandemic: a single-center report

AK Bankova, J Caveney, B Yao, TL Ramos… - … and Cellular Therapy, 2022 - Elsevier
In response to the widespread COVID-19 pandemic, cryopreservation of allogeneic donor
apheresis products was implemented to mitigate the challenges of donor availability and …

Impact of cryopreservation of peripheral blood stem cells (PBSC) in transplantation from matched unrelated donor (MUD)

G Facchin, C Savignano, ML Battista, M Isola… - Journal of Clinical …, 2022 - mdpi.com
Background: Cryopreservation of PBSC for allogenic hematopoietic stem cell transplantation
(allo-HSCT) was implemented due to the current Coronavirus 2019 pandemic. The impact of …

Leukocytapheresis variables and transit time for allogeneic cryopreserved hpc: better safe than sorry

J Fernandez-Sojo, R Horton, J Cid, C Azqueta… - Bone Marrow …, 2022 - nature.com
Cryopreservation was recommended to ensure continuity in allogeneic hematopoietic
progenitor cells (HPC) transplantation during the COVID-19 pandemic. Several groups have …

Coordinated immune cell networks in the bone marrow microenvironment define the graft versus leukemia response with adoptive cellular therapy

A Maurer, CY Park, S Mani, M Borji, C Shin, L Penter… - Blood, 2023 - Elsevier
Donor lymphocyte infusion (DLI) is an established therapy for relapsed acute myeloid
leukemia (AML) after hematopoietic stem cell transplant (HSCT), but response rates are …