The optimal timing of aortic valve replacement (AVR) remains controversial. Several
biomarkers reflect the underlying pathophysiological processes in aortic stenosis (AS) and …

Aortic stenosis (AS) is the most frequent valvular heart disease among the older individuals.
Current guidelines indicate intervention for patients with symptomatic or fast progressive …

Background Previous studies have mainly focused more on how diabetes affects the valve
than the myocardium in aortic stenosis (AS). In the pressure-overloaded heart, myocardial …

Patients with severe aortic valve stenosis and concomitant pulmonary hypertension show a
significantly reduced survival prognosis. Right heart catheterization as a preoperative …

Background: Frailty is an important outcome predictor in patients with aortic stenosis who
are candidates for transcatheter or surgical aortic valve replacement (AVR) …

Aims: Palmitic acid (PA) and oleic acid (OA) are two main dietary fatty acids. Dietary intake of
PA has been associated with cardiovascular disease risk, and the effect of OA remains …

Objective: Trimethylamine N-oxide (TMAO), a pathological microbial metabolite, is
demonstrated to be related to cardiovascular diseases. This study was (1) to investigate the …

(1) Background: Currently, echocardiography is the primary non-invasive diagnostic method
used to screen patients with severe aortic valve stenosis (AS) for pulmonary hypertension …

Objectives To determine whether baseline C‐reactive protein (CRP) levels can predict
mortality after transcatheter aortic valve implantation (TAVI), we performed a meta‐analysis …

Background A blood multimarker approach may be useful to enhance risk stratification in
patients undergoing TAVI. Objectives The objective of this study was to determine the …