Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

In analogy to split-protein systems, which rely on the appropriate fragmentation of protein
domains, split aptamers made of two or more short nucleic acid strands have emerged as …

The E. coli transcriptome at the cell's poles (polar transcriptome) is unique compared to the
membrane and cytosol. Several factors have been suggested to mediate mRNA localization …

The rise in fluorescence-based imaging techniques over the past 3 decades has improved
the ability of researchers to scrutinize live cell biology at increased spatial and temporal …

Only recently has it been recognized that the transcriptome of bacteria and archaea can be
spatiotemporally regulated. All types of prokaryotic transcripts—rRNAs, tRNAs, mRNAs, and …

Diverse mechanisms and functions of posttranscriptional regulation by small regulatory
RNAs and RNA-binding proteins have been described in bacteria. In contrast, little is known …

One of the most important discoveries in the field of microbiology in the last two decades is
that bacterial cells have intricate subcellular organization. This understanding has emerged …

RNA presents intringuing roles in many cellular processes and its versatility underpins many
different applications in synthetic biology. Nonetheless, RNA origami as a method for …

Only a few short decades have passed since the sequencing of GFP, yet the modern
repertoire of transgenically encoded optical tools implies an exponential proliferation of ever …

To be able to visualize the abundance and spatiotemporal features of RNAs in bacterial
cells would permit obtaining a pivotal understanding of many mechanisms underlying …