Objective and methods Worldwide, tuberculosis (TB) is the leading cause of death from a
single infectious agent. In many countries, national TB prevalence surveys are the only way …

We performed the first studies of analytic sensitivity, analytic specificity, and dynamic range
for the new Xpert MTB/RIF assay, a nucleic acid amplification-based diagnostic system that …

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available
antibiotics, and requires new approaches to antibiotic discovery and development …

Background and objectives: Multidrug resistant (MDR) bacteria are a growing threat to
global health. Studies focusing on single antibiotics have shown that drug resistance is often …

Phenylboronic acid functionalized high-crystallinity fluorescent covalent organic framework
(BA@ COF), which can be applied for rifamycin antibiotics and water sensing, and for …

Abstract Development of excellent sensors to determine trace concentrations of rifampicin is
of intense importance for medicine analysis and human health. Herein, a facile and green …

Abstract Objectives Three Mycobacterium tuberculosis genetic loci—rpoB and katG genes
and the fabG1 (mabA)–inhA operon promoter region—were studied to reveal the mutations …

Background Tuberculosis (TB) is a major health problem and HIV is the major cause of the
increase in TB. Sub-Saharan Africa is endemic for both TB and HIV infection. Determination …

Background Developments in molecular detection and strain differentiation of members of
Mycobacterium tuberculosis complex have proved to be useful. The DNA extraction method …

Despite being genetically monomorphic, the limited genetic diversity within the
Mycobacterium tuberculosis complex (MTBC) has practical consequences for molecular …