Macrophage migration inhibitory factor (MIF): a multifaceted cytokine regulated by genetic and physiological strategies
K Sumaiya, D Langford, K Natarajaseenivasan… - Pharmacology & …, 2022 - Elsevier
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
The pathogenic role of angiogenesis in rheumatoid arthritis
HA Elshabrawy, Z Chen, MV Volin, S Ravella… - Angiogenesis, 2015 - Springer
Angiogenesis is the formation of new capillaries from pre-existing vasculature, which plays a
critical role in the pathogenesis of several inflammatory autoimmune diseases such as …
critical role in the pathogenesis of several inflammatory autoimmune diseases such as …
Evolving complexity of MIF signaling
Macrophage migration inhibitory factor (MIF) is a cytokine expressed in various cell types,
including hematopoietic, epithelial, endothelial, mesenchymal and neuronal cells. Altered …
including hematopoietic, epithelial, endothelial, mesenchymal and neuronal cells. Altered …
Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor
GS Ashcroft, SJ Mills, KJ Lei, L Gibbons… - The Journal of …, 2003 - Am Soc Clin Investig
Characteristic of both chronic wounds and acute wounds that fail to heal are excessive
leukocytosis and reduced matrix deposition. Estrogen is a major regulator of wound repair …
leukocytosis and reduced matrix deposition. Estrogen is a major regulator of wound repair …
Macrophage migration inhibitory factor in cardiovascular disease
A Zernecke, J Bernhagen, C Weber - Circulation, 2008 - Am Heart Assoc
The highly conserved and archetypical yet atypical cytokine macrophage migration
inhibitory factor (MIF) fulfills pleiotropic immune functions in many acute and chronic …
inhibitory factor (MIF) fulfills pleiotropic immune functions in many acute and chronic …
Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis
A Burger-Kentischer, H Goebel, R Seiler, G Fraedrich… - Circulation, 2002 - Am Heart Assoc
Background—Atherosclerosis is a chronic inflammatory response of the arterial wall to
injury. Macrophage migration inhibitory factor (MIF), a cytokine with potent inflammatory …
injury. Macrophage migration inhibitory factor (MIF), a cytokine with potent inflammatory …
Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids
Objective Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine whose
involvement in tumor necrosis factor α (TNFα) synthesis and T cell activation suggests a role …
involvement in tumor necrosis factor α (TNFα) synthesis and T cell activation suggests a role …
Inflammation and cancer: macrophage migration inhibitory factor (MIF)—the potential missing link
H Conroy, L Mawhinney… - QJM: An International …, 2010 - academic.oup.com
Macrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50
years ago and has since been revealed to be an important player in pro-inflammatory …
years ago and has since been revealed to be an important player in pro-inflammatory …
The hormonal regulation of cutaneous wound healing
SC Gilliver, JJ Ashworth, GS Ashcroft - Clinics in dermatology, 2007 - Elsevier
Conditions of impaired wound healing in the elderly are associated with substantial
morbidity and mortality and impose a significant financial burden upon the world's health …
morbidity and mortality and impose a significant financial burden upon the world's health …
The pathophysiology of falciparum malaria
IA Clark, WB Cowden - Pharmacology & therapeutics, 2003 - Elsevier
Falciparum malaria is a complex disease with no simple explanation, affecting organs where
the parasite is rare as well as those organs where it is more common. We continue to argue …
the parasite is rare as well as those organs where it is more common. We continue to argue …