It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …

A wide range of insults can trigger axon degeneration, and axons respond with diverse
morphology, topology and speed. However, recent genetic, immunochemical, morphological …

The diagnostic reliability of skin biopsy in small fiber neuropathy depends on the availability
of normative reference values. We performed a multicenter study to assess the normative …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Erythropoietin (EPO) is both hematopoietic and tissue protective, putatively through
interaction with different receptors. We generated receptor subtype–selective ligands …

Background Although vascular endothelial growth factor (VEGF) is a primary mediator of
retinal angiogenesis, VEGF inhibition alone is insufficient to prevent retinal …

Long-term diabetes increases the likelihood of developing secondary damage to numerous
systems, and these complications represent a substantial cause of morbidity and mortality …

Erythropoietin mediates an evolutionarily conserved, ancient immune response that limits
damage to the heart, the nervous system and other tissues following injury. New evidence …

In the haematopoietic system, the principal function of erythropoietin (Epo) is the regulation
of red blood cell production, mediated by its specific cell surface receptor (EpoR). Following …

Erythropoietin (EPO) increases the number of circulating erythrocytes primarily by
preventing apoptosis of erythroid progenitors. In addition to this proerythroid action, results …