Sex differences in cardiovascular pathophysiology: why women are overrepresented in heart failure with preserved ejection fraction

AL Beale, P Meyer, TH Marwick, CSP Lam, DM Kaye - Circulation, 2018 - Am Heart Assoc
Consistent epidemiological data demonstrate that patients with heart failure with preserved
ejection fraction (HFpEF) are more likely to be women than men. Exploring mechanisms …

Mechanistic pathways of sex differences in cardiovascular disease

V Regitz-Zagrosek, G Kararigas - Physiological reviews, 2016 - journals.physiology.org
Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

Sex-related differences in myocardial remodeling

M Piro, R Della Bona, A Abbate, LM Biasucci… - Journal of the American …, 2010 - jacc.org
Sex has a profound impact on myocardial remodeling, which is defined as the molecular
and cellular events after an injury to the myocardium (ie, necrosis, pressure overload …

Heart failure subtypes and cardiomyopathies in women

EM DeFilippis, A Beale, T Martyn, A Agarwal… - Circulation …, 2022 - Am Heart Assoc
Heart failure affects over 2.6 million women and 3.4 million men in the United States with
known sex differences in epidemiology, management, response to treatment, and outcomes …

Sex-specific influence on cardiac structural remodeling and therapy in cardiovascular disease

EL Kessler, MR Rivaud, MA Vos… - Biology of Sex …, 2019 - Springer
Abstract Background Cardiovascular diseases (CVDs) culminating into heart failure (HF) are
major causes of death in men and women. Prevalence and manifestation, however, differ …

Cardiac imaging after myocardial infarction

FA Flachskampf, M Schmid, C Rost… - European heart …, 2011 - academic.oup.com
After myocardial infarction, optimal clinical management depends critically on cardiac
imaging. Remodelling and heart failure, presence of inducible ischaemia, presence of …

[HTML][HTML] Sex and gender differences in heart failure

V Regitz-Zagrosek - International journal of heart failure, 2020 - ncbi.nlm.nih.gov
Heart failure (HF) phenotypes differ according to sex. HF preserved ejection fraction (EF)
has a greater prevalence in women and HF reduced EF (HFrEF) in men. Women with HF …

Genetic, molecular, and cellular determinants of sex-specific cardiovascular traits

F Vaura, J Palmu, J Aittokallio, A Kauko… - Circulation …, 2022 - Am Heart Assoc
Despite the well-known sex dimorphism in cardiovascular disease traits, the exact genetic,
molecular, and cellular underpinnings of these differences are not well understood. A …

Sex differences in cardiovascular aging and heart failure

A Oneglia, MD Nelson, CNB Merz - Current heart failure reports, 2020 - Springer
Abstract Purpose of the Review This review summarizes sex-related changes in the heart
and vasculature that occur with aging, both in the presence and absence of cardiovascular …

Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction

P Mohindra, JX Zhong, Q Fang, DL Cuylear… - NPJ Regenerative …, 2023 - nature.com
Heart failure (HF) remains a global public health burden and often results following
myocardial infarction (MI). Following injury, cardiac fibrosis forms in the myocardium which …