Addressing the in vivo delivery of nucleic-acid nanostructure therapeutics
DNA and RNA nanostructures are being investigated as therapeutics, vaccines, and drug
delivery systems. These nanostructures can be functionalized with guests ranging from …
delivery systems. These nanostructures can be functionalized with guests ranging from …
Insights in the host response towards biomaterial-based scaffolds for cancer therapy
Immunotherapeutic strategies have shown promising results in the treatment of cancer.
However, not all patients respond, and treatments can have severe side-effects. Adoptive …
However, not all patients respond, and treatments can have severe side-effects. Adoptive …
Injectable hydrogel based on protein-polyester microporous network as an implantable niche for active cell recruitment
Despite the potential of hydrogel-based localized cancer therapies, their efficacy can be
limited by cancer recurrence. Therefore, it is of great significance to develop a hydrogel …
limited by cancer recurrence. Therefore, it is of great significance to develop a hydrogel …
Biodegradable scaffolds for enhancing vaccine delivery
Sustained release of vaccine components is a potential method to boost efficacy compared
with traditional bolus injection. Here, we show that a biodegradable hyaluronic acid (HA) …
with traditional bolus injection. Here, we show that a biodegradable hyaluronic acid (HA) …
Macrophage-hitchhiking Anisotropic Microparticles for Therapeutic and Diagnostic Applications
LW Wang - 2023 - dspace.mit.edu
Cell therapies represent a major paradigm shift of biotechnology in medicine due to its
transformative potential in treating previously incurable diseases. A variety of cells have …
transformative potential in treating previously incurable diseases. A variety of cells have …