Cerebrospinal fluid immune markers and HIV-associated neurocognitive impairments: A systematic review

ME Williams, DJ Stein, JA Joska, PJW Naudé - Journal of …, 2021 - Elsevier
HIV-1 is responsible for the development of a spectrum of cognitive impairments known as
HIV-associated neurocognitive disorder (HAND). In the era of antiretroviral therapy (ART) …

Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy

Y Zhang, Y Long, J Wan, S Liu, A Shi, D Li… - Journal of Drug …, 2023 - Taylor & Francis
In recent years, there have been many exciting developments in the biomedical applications
of the macrophage membrane bionic drug delivery system (MM-Bio-DDS). Macrophages, as …

Interaction of BDNF and cytokines in executive dysfunction in patients with chronic schizophrenia

MH Xiu, DM Wang, XD Du, N Chen, SP Tan… - …, 2019 - Elsevier
Multiple lines of evidence indicate that patients with chronic schizophrenia (SCZ) display
executive dysfunction across the illness course. However, the potential molecular …

Peripheral immune dysregulation in the ART era of HIV-associated neurocognitive impairments: A systematic review

ME Williams, JC Ipser, DJ Stein, JA Joska… - …, 2020 - Elsevier
Human immunodeficiency virus-associated neurocognitive impairment (HANI) remains
problematic despite the effective use of antiretroviral therapy (ART) and viral suppression. A …

The Potential of Moringa oleifera to Ameliorate HAART-Induced Pathophysiological Complications

SS Ndlovu, T Ghazi, AA Chuturgoon - Cells, 2022 - mdpi.com
Highly active antiretroviral therapy (HAART) comprises a combination of two or three
antiretroviral (ARV) drugs that are administered together in a single tablet. These drugs …

Optimal treatment of HIV-associated neurocognitive disorders: myths and reality. A critical review

A Bougea, N Spantideas, P Galanis… - Therapeutic …, 2019 - journals.sagepub.com
Background: The aim of this study was to review the clinical data on the effectiveness of the
pharmacotherapy of HIV-associated neurocognitive disorders (HANDs). Methods: A …

The impact of antiretroviral therapy on neurocognitive outcomes among people living with HIV in low-and middle-income countries (LMICs): a systematic review

HU Michael, S Naidoo, KB Mensah, S Ramlall… - AIDS and Behavior, 2021 - Springer
Low and middle-income countries (LMICs) are the epicenter of the HIV epidemic. The scale-
up of antiretroviral therapy (ART) has reduced mortality, but HIV-associated neurocognitive …

The role of brain derived neurotrophic factor in HIV-associated neurocognitive disorder: From the bench-top to the bedside

H Michael, T Mpofana, S Ramlall… - … Disease and Treatment, 2020 - Taylor & Francis
Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) remains
prevalent in the anti-retroviral (ART) era. While there is a complex interplay of many factors …

The association of peripheral immune markers with brain cortical thickness and surface area in South African people living with HIV

ME Williams, JA Joska, AR Amod, RH Paul… - Journal of …, 2020 - Springer
A spectrum of cognitive impairments known as HIV-associated neurocognitive disorders
(HAND) are consequences of the effects of HIV-1 within the central nervous system …

Serum Mature and Precursor Brain-Derived Neurotrophic Factors and Their Association with Neurocognitive Function in ART-Naïve Adults Living with HIV in Sub …

HU Michael, AM Rapulana, T Smit, N Xulu… - Molecular …, 2024 - Springer
This study investigates the association between serum mature brain-derived neurotrophic
factor (mBDNF), its precursor proBDNF, and neurocognitive function in ART-naïve adults …