Stimuli‐responsive nanocomposite hydrogels for biomedical applications

P Lavrador, MR Esteves, VM Gaspar… - Advanced Functional …, 2021 - Wiley Online Library
The complex tissue‐specific physiology that is orchestrated from the nano‐to the
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …

Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Designing hydrogels for controlled drug delivery

J Li, DJ Mooney - Nature Reviews Materials, 2016 - nature.com
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery

HX Wang, M Li, CM Lee, S Chakraborty… - Chemical …, 2017 - ACS Publications
Genome editing offers promising solutions to genetic disorders by editing DNA sequences
or modulating gene expression. The clustered regularly interspaced short palindromic …

Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management

S Jacob, AB Nair, J Shah, N Sreeharsha, S Gupta… - Pharmaceutics, 2021 - mdpi.com
The popularity of hydrogels as biomaterials lies in their tunable physical properties, ability to
encapsulate small molecules and macromolecular drugs, water holding capacity, flexibility …

[HTML][HTML] Various methods of gold nanoparticles (GNPs) conjugation to antibodies

MH Jazayeri, H Amani, AA Pourfatollah… - Sensing and bio …, 2016 - Elsevier
The unique properties of gold nanoparticles, their rich surface chemistry, and low toxicity as
well as easy methods of synthesis have promoted conjugation of the particles with …

Current state of knowledge on intelligent-response biological and other macromolecular hydrogels in biomedical engineering: A review

M Su, L Ruan, X Dong, S Tian, W Lang, M Wu… - International Journal of …, 2023 - Elsevier
Because intelligent hydrogels have good biocompatibility, a rapid response, and good
degradability as well as a stimulus response mode that is rich, hydrophilic, and similar to the …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

RNA-polymer hybrids via direct and site-selective acylation with the ATRP initiator and photoinduced polymerization

J Jeong, X Hu, H Murata, G Szczepaniak… - Journal of the …, 2023 - ACS Publications
Combining synthetic polymers with RNA paves the way for creating RNA-based materials
with non-canonical functions. We have developed an acylation reagent that allows for direct …