“Sticki-ER”: Functions of the Platelet Endoplasmic Reticulum
Significance: The primary role of platelets is to generate a thrombus by platelet activation.
Platelet activation relies on calcium mobilization from the endoplasmic reticulum (ER). ER …
Platelet activation relies on calcium mobilization from the endoplasmic reticulum (ER). ER …
Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and …
N Garbrecht, M Anlauf, A Schmitt… - Endocrine-Related …, 2008 - erc.bioscientifica.com
Somatostatin-producing neuroendocrine tumors (SOM-NETs) of the duodenum and
pancreas appear to be heterogeneous. To determine their clinicopathological profiles …
pancreas appear to be heterogeneous. To determine their clinicopathological profiles …
Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation
A Spyropoulou, A Gargalionis, G Dalagiorgou… - Neuromolecular …, 2014 - Springer
Posttranslational modifications of histones are considered as critical regulators of gene
expression, playing significant role in the pathogenesis and progression of tumors …
expression, playing significant role in the pathogenesis and progression of tumors …
Molecular chaperone ERp29: a potential target for cellular protection in retinal and neurodegenerative diseases
T McLaughlin, M Falkowski, JJ Wang… - … and Experimental Therapy, 2018 - Springer
The molecular chaperone endoplasmic reticulum protein 29 (ERp29) plays a critical role in
protein folding, trafficking, and secretion. Though ubiquitously expressed, ERp29 is …
protein folding, trafficking, and secretion. Though ubiquitously expressed, ERp29 is …
Three-dimensional protein fold determination from backbone amide pseudocontact shifts generated by lanthanide tags at multiple sites
H Yagi, KB Pilla, A Maleckis, B Graham, T Huber… - Structure, 2013 - cell.com
Site-specific attachment of paramagnetic lanthanide ions to a protein generates
pseudocontact shifts (PCS) in the nuclear magnetic resonance (NMR) spectra of the protein …
pseudocontact shifts (PCS) in the nuclear magnetic resonance (NMR) spectra of the protein …
Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis
G Dalagiorgou, C Piperi, C Adamopoulos… - Cellular and Molecular …, 2017 - Springer
Abstract Polycystin-1 (PC1) has been proposed as a chief mechanosensing molecule
implicated in skeletogenesis and bone remodeling. Mechanotransduction via PC1 involves …
implicated in skeletogenesis and bone remodeling. Mechanotransduction via PC1 involves …
ERp29 deficiency affects sensitivity to apoptosis via impairment of the ATF6–CHOP pathway of stress response
I Hirsch, M Weiwad, E Prell, DM Ferrari - Apoptosis, 2014 - Springer
Abstract Endoplasmic reticulum protein 29 (ERp29) belongs to the redox-inactive PDI-Dβ-
subfamily of PDI-proteins. ERp29 is expressed in all mammalian tissues examined …
subfamily of PDI-proteins. ERp29 is expressed in all mammalian tissues examined …
The probable, possible, and novel functions of ERp29
M Brecker, S Khakhina, TJ Schubert… - Frontiers in …, 2020 - frontiersin.org
The luminal endoplasmic reticulum (ER) protein of 29 kDa (ERp29) is a ubiquitously
expressed cellular agent with multiple critical roles. ERp29 regulates the biosynthesis and …
expressed cellular agent with multiple critical roles. ERp29 regulates the biosynthesis and …
Disruption of protein processing in the endoplasmic reticulum of DYT1 knock-in mice implicates novel pathways in dystonia pathogenesis
G Beauvais, NM Bode, JL Watson, H Wen… - Journal of …, 2016 - Soc Neuroscience
Dystonia type 1 (DYT1) is a dominantly inherited neurological disease caused by mutations
in TOR1A, the gene encoding the endoplasmic reticulum (ER)-resident protein torsinA …
in TOR1A, the gene encoding the endoplasmic reticulum (ER)-resident protein torsinA …
Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis
G Dalagiorgou, C Piperi, U Georgopoulou… - Cellular and molecular …, 2013 - Springer
Mechanical forces trigger biological responses in bone cells that ultimately control
osteoblastogenesis and bone program. Although several mechanosensors have been …
osteoblastogenesis and bone program. Although several mechanosensors have been …