[HTML][HTML] Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …

Repurposing pentoxifylline for the treatment of fibrosis: an overview

WX Wen, SY Lee, R Siang, RY Koh - Advances in Therapy, 2017 - Springer
Fibrosis is a potentially debilitating disease with high morbidity rates. It is estimated that half
of all deaths that occur in the USA are attributed to fibrotic disorders. Fibrotic disorders are …

Regulatory T cells promote β-catenin–mediated epithelium-to-mesenchyme transition during radiation-induced pulmonary fibrosis

S Xiong, X Pan, L Xu, Z Yang, R Guo, Y Gu, R Li… - International Journal of …, 2015 - Elsevier
Purpose Radiation-induced pulmonary fibrosis results from thoracic radiation therapy and
severely limits radiation therapy approaches. CD4+ CD25+ FoxP3+ regulatory T cells …

Treg depletion attenuates irradiation-induced pulmonary fibrosis by reducing fibrocyte accumulation, inducing Th17 response, and shifting IFN-γ, IL-12/IL-4, IL-5 …

S Xiong, R Guo, Z Yang, L Xu, L Du, R Li, F Xiao… - Immunobiology, 2015 - Elsevier
Irradiation-induced pulmonary fibrosis results from thoracic radiotherapy and severely limits
radiotherapy approaches. CD4+ CD25+ FoxP3+ regulatory T cells (Tregs) are involved in …

Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy

V Patel, M McGurk - British Journal of Oral and Maxillofacial Surgery, 2017 - Elsevier
Radiation-induced fibrosis in the head and neck is a well-established pathophysiological
process after radiotherapy. Recently pentoxifylline and tocopherol have been proposed as …

[HTML][HTML] Roles of sulfur metabolism and rhodanese in detoxification and anti-oxidative stress functions in the liver: responses to radiation exposure

T Nakajima - … science monitor: international medical journal of …, 2015 - ncbi.nlm.nih.gov
Organisms must confront various environmental stresses. The liver is central to protecting
against such stresses in mammals, and it has many detoxification and anti-oxidative stress …

Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing …

S Shrishrimal, A Chatterjee, EA Kosmacek… - Free Radical Biology …, 2020 - Elsevier
Radiation therapy is a frequently used treatment for prostate cancer patients. Manganese
(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnTE-2-PyP or T2E or BMX-010) and …

[HTML][HTML] Therapeutic potential of the combination of pentoxifylline and vitamin-E in inflammatory bowel disease: Inhibition of intestinal fibrosis

HJ Lee - Journal of Clinical Medicine, 2022 - mdpi.com
Background: Although intestinal fibrosis is a consequence of recurrent inflammation in
Inflammatory bowel disease (IBD), alleviating inflammation alone does not prevent the …

[HTML][HTML] Pentoxifylline inhibits pulmonary fibrosis by regulating cellular senescence in mice

Y Lin, Z Xu, B Zhou, K Ma, M Jiang - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease, and its occurrence and
development are mediated by cellular senescence. Drugs targeting senescent cells seem …

Effects of supplementation of vitamins D, C and E on idiopathic pulmonary fibrosis (IPF): a clinical trial

M Yavari, SAJ Mousavi, L Janani, Z Feizy… - Clinical Nutrition ESPEN, 2022 - Elsevier
Background & aims Idiopathic pulmonary fibrosis (IPF) is a chronic disease with a growing
prevalence. We aimed to evaluate the effects of co-supplementation with vitamins C, E, and …