Triazole derivatives and their antiplasmodial and antimalarial activities
XM Chu, C Wang, WL Wang, LL Liang, W Liu… - European journal of …, 2019 - Elsevier
Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …
Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review
Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …
Green synthesis and anticancer potential of chalcone linked-1, 2, 3-triazoles
A series of chalcone linked-1, 2, 3-triazoles was synthesized via cellulose supported copper
nanoparticle catalyzed click reaction in water. The structures of all the compounds were …
nanoparticle catalyzed click reaction in water. The structures of all the compounds were …
Ferrocene-appended pharmacophores: An exciting approach for modulating the biological potential of organic scaffolds
Two exemplary contributions of organometallics in medicinal chemistry, ferroquine and
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …
Combination therapy strategies for the treatment of malaria
S Alven, B Aderibigbe - Molecules, 2019 - mdpi.com
Malaria is a vector-and blood-borne infection that is responsible for a large number of
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …
Current scenario of ferrocene-containing hybrids for antimalarial activity
J Xiao, Z Sun, F Kong, F Gao - European Journal of Medicinal Chemistry, 2020 - Elsevier
Hybrid molecules have the potential to enhance the efficacy against both drug-sensitive and
drug-resistant organisms, and Ferroquine, a ferrocene hybrid, has demonstrated great …
drug-resistant organisms, and Ferroquine, a ferrocene hybrid, has demonstrated great …
[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …
compound by combining two or more pharmacophoric units. Being a linkage process, it …
1H-1, 2, 3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation
K Kumar, B Pradines, M Madamet, R Amalvict… - European journal of …, 2014 - Elsevier
Abstract 1H-1, 2, 3-triazole tethered isatin-ferrocene conjugates were synthesized and
evaluated for their antiplasmodial activities against chloroquine-susceptible (3D7) and …
evaluated for their antiplasmodial activities against chloroquine-susceptible (3D7) and …
Roles of virtual screening and molecular dynamics simulations in discovering and understanding antimalarial drugs
Malaria continues to be a global health threat, with approximately 247 million cases
worldwide. Despite therapeutic interventions being available, patient compliance is a …
worldwide. Despite therapeutic interventions being available, patient compliance is a …
A strategic approach to the synthesis of ferrocene appended chalcone linked triazole allied organosilatranes: Antibacterial, antifungal, antiparasitic and antioxidant …
G Singh, A Arora, P Kalra, IK Maurya, CE Ruizc… - Bioorganic & Medicinal …, 2019 - Elsevier
A series of ferrocene appended chalcone allied triazole coupled organosilatranes (FCTSa 7–
FCTSa 12) were synthesised with the aim of amalgamating the pharmacological action of …
FCTSa 12) were synthesised with the aim of amalgamating the pharmacological action of …