Inflammation is the body's way of defending itself against noxious stimuli and pathogens.
Under normal circumstances, the body is able to eliminate the insult and subsequently …

Annexin‐A1 has a well‐defined anti‐inflammatory role in the innate immune system, but its
function in adaptive immunity remains controversial. This glucocorticoid‐induced protein has …

N-formyl peptide receptors (FPRs) are critical regulators of host defense in phagocytes and
are also expressed in epithelia. FPR signaling and function have been extensively studied …

The 37‐kDa protein annexin 1 (Anx‐1; lipocortin 1) has been implicated in the regulation of
phagocytosis, cell signaling, and proliferation and is postulated to be a mediator of …

Background: Heart failure following myocardial infarction (MI) remains one of the major
causes of death worldwide, and its treatment is a crucial challenge of cardiovascular …

Excessive inflammation and failed resolution of the inflammatory response are underlying
components of numerous conditions such as arthritis, cardiovascular disease, and cancer …

We have tested the effects of annexin 1 (ANXA1) and its N-terminal peptide Ac2-26 on
polymorphonuclear leukocyte (PMN) recruitment under flow. Differential effects of the full …

Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates
(some of the) anti-inflammatory effects of glucocorticoids. Subsequently, the role of ANXA1 …

The glucocorticoids are the most potent anti‐inflammatory drugs that we possess and are
effective in a wide variety of diseases. Although their action is known to involve receptor …

Effective treatment for managing myocardial infarction (MI) remains an urgent, unmet clinical
need. Formyl peptide receptors (FPR) regulate inflammation, a major contributing …