Calcific aortic stenosis is a progressive disease with no effective medical therapy that
ultimately requires aortic valve replacement (AVR) for severe valve obstruction …

Acute cardiovascular dysfunction occurs perioperatively in more than 20% of cardiosurgical
patients, yet current acute heart failure (HF) classification is not applicable to this period …

Background—Global longitudinal systolic strain (GLS) is often reduced in aortic stenosis
despite normal ejection fraction. The importance of reduced preoperative GLS on long-term …

Aortic stenosis (AS) is now the most common indication for valve replacement in Europe and
North America, with an ever increasing disease prevalence due to the ageing population …

Calcific aortic valve disease (CAVD) is a highly prevalent cardiovascular disorder
accounting for a rising economic and social burden on aging populations. In spite of …

The optimal timing of valve surgery remains controversial. Biomarkers can be serially
monitored and are objective laboratory measurements. Plasma B-type natriuretic peptide …

BACKGROUND: The European System for Cardiac Operative Risk Evaluation
(EuroSCORE) was developed to predict immediate outcomes after adult cardiac operations …

Surgical morbidity is a significant public health issue worldwide. It is estimated that 230
million surgical procedures are performed each year, with an estimated mortality of at least …

The optimal timing of aortic valve replacement (AVR) remains controversial. Several
biomarkers reflect the underlying pathophysiological processes in aortic stenosis (AS) and …

Calcific aortic valve disease (CAVD) is the most common acquired valvular disorder in
developed countries. CAVD ranges from mild thickening of the valve, known as aortic valve …