The yeast cell wall is a strong, but elastic, structure that is essential not only for the
maintenance of cell shape and integrity, but also for progression through the cell cycle …

The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in
human cells makes this component an attractive target for antifungal development. The host …

Chitin is an essential part of the carbohydrate skeleton of the fungal cell wall and is a
molecule that is not represented in humans and other vertebrates. Complex regulatory …

Chitin is a polymer of N-acetylglucosamine, which assembles into microfibrils of about 20
sugar chains. These microfibrils serve as a structural component of natural biocomposites …

The echinocandins are the newest class of antifungal agents in the clinical armory. These
secondary metabolites are non-competitive inhibitors of the synthesis of β-(1, 3)-glucan, a …

Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …

Biologists have long used model organisms to study human diseases, particularly when the
model bears a close resemblance to the disease. We present a method that quantitatively …

Mitogen-activated protein kinase (MAPK) cascades and the calcium–calcineurin pathway
control fundamental aspects of fungal growth, development and reproduction. Core …

Fungi occupy diverse environments and are subjected to many extreme conditions. Among
the stressful conditions faced by fungi are pH changes, osmotic changes, thermal changes …

Fungi are surrounded by an essential structure, the cell wall, which not only confers cell
shape but also protects cells from environmental stress. As a consequence, yeast cells …