The availability of highly active antiretroviral therapies (HAART) has not eliminated HIV-1
infection of the central nervous system (CNS) or the occurrence of HIV-associated …

This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Almost 7 million children under the age 5 die each year, and most of these deaths are
attributable to vaccine-preventable infections. Young infants respond poorly to infections …

Complex dosing regimens, costs, side effects, biodistribution limitations, and variable drug
pharmacokinetic patterns have affected the long-term efficacy of antiretroviral medicines. To …

Background In endemic areas, placental malaria due to Plasmodium falciparum is most
frequent and severe in first-time mothers, and increases the risk of infant mortality in their …

Background Assumptions about survival of HIV-infected children in Africa without
antiretroviral therapy need to be updated to inform ongoing UNAIDS modelling of paediatric …

HIV in children is a serious and growing problem in sub-Saharan Africa. At present very little
is known about the neurological complications of human immunodeficiency virus (HIV) …

Objective: To estimate the effect of delaying antiretroviral treatment (ART) for 15, 30, or 60
days after tuberculosis (TB) treatment initiation on mortality and virological suppression …

The human immunodeficiency virus (HIV) was unknown until the early 1980's when
increasing numbers of cases of unusual opportunistic infections and Kaposi sarcoma in …

Infant humans and rhesus macaques infected with the human or simian immunodeficiency
virus (HIV or SIV), respectively, express higher viral loads and progress more rapidly to AIDS …