Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Synaptic effects induced by alcohol

DM Lovinger, M Roberto - 2023 - Springer
Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in
synaptic function are prominent among these effects. Acute exposure to EtOH activates or …

Targeting glutamate uptake to treat alcohol use disorders

PSS Rao, RL Bell, EA Engleman, Y Sari - Frontiers in neuroscience, 2015 - frontiersin.org
Alcoholism is a serious public health concern that is characterized by the development of
tolerance to alcohol's effects, increased consumption, loss of control over drinking and the …

Increased basolateral amygdala pyramidal cell excitability may contribute to the anxiogenic phenotype induced by chronic early-life stress

AR Rau, AM Chappell, TR Butler… - Journal of …, 2015 - Soc Neuroscience
Adolescence represents a particularly vulnerable period during which exposure to stressors
can precipitate the onset of psychiatric disorders and addiction. The basolateral amygdala …

Regional gray matter deficits in alcohol dependence: A meta-analysis of voxel-based morphometry studies

PR Xiao, ZY Dai, JG Zhong, YL Zhu, HC Shi… - Drug and alcohol …, 2015 - Elsevier
Background Many studies have revealed a widespread pattern of gray matter (GM) atrophy
by using voxel-based morphometry (VBM) studies involving the pathophysiology of alcohol …

Repeated binge-like ethanol drinking alters ethanol drinking patterns and depresses striatal GABAergic transmission

MV Wilcox, VCC Carlson, N Sherazee… - …, 2014 - nature.com
Repeated cycles of binge alcohol drinking and abstinence are key components in the
development of dependence. However, the precise behavioral mechanisms underlying …

Probiotics-based treatment as an integral approach for alcohol use disorder in alcoholic liver disease

C Fuenzalida, MS Dufeu, J Poniachik… - Frontiers in …, 2021 - frontiersin.org
Alcoholic liver disease (ALD) is one of the leading causes of morbidity among adults with
alcohol use disorder (AUD) worldwide. Its clinical course ranges from steatosis to alcoholic …

Deep brain stimulation for psychiatric disorders: where we are now

DR Cleary, A Ozpinar, AM Raslan, AL Ko - Neurosurgical focus, 2015 - thejns.org
Fossil records showing trephination in the Stone Age provide evidence that humans have
sought to influence the mind through physical means since before the historical record …

Psychological and neurobiological correlates of food addiction

E Kalon, JY Hong, C Tobin, T Schulte - International review of neurobiology, 2016 - Elsevier
Food addiction (FA) is loosely defined as hedonic eating behavior involving the
consumption of highly palatable foods (ie, foods high in salt, fat, and sugar) in quantities …

Stress-induced red nucleus attenuation induces anxiety-like behavior and lymph node CCL5 secretion

DD Shi, YD Zhang, S Zhang, BB Liao, MY Chu… - Nature …, 2023 - nature.com
Previous studies have speculated that brain activity directly controls immune responses in
lymphoid organs. However, the upstream brain regions that control lymphoid organs and …