Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Programmed cell death (PCD) pathways, including apoptosis and regulated necrosis, are
required for normal cell turnover and tissue homeostasis. Mis-regulation of PCD is …

Cellular senescence has been shown to contribute to skin ageing. However, the role of
melanocytes in the process is understudied. Our data show that melanocytes are the only …

In wound healing, individual cells' behaviors coordinate movement toward the wound center
to restore small or large barrier defects. The migration of epithelial cells as a continuous …

The skin barrier is mainly present in the stratum corneum (SC), composed of corneocytes
surrounded by intercellular lipid lamellae, and attached by corneodesmosome. The tight …

Marine algae are considered to be an abundant sources of bioactive compounds with
cosmeceutical potential. Recently, a great deal of interest has focused on the health …

Type XVII collagen (COL17) is a transmembrane protein located at the epidermal basement
membrane zone. COL17 deficiency results in premature hair aging phenotypes and in …

Background Atopic dermatitis (AD) is a multifactorial and complex disease, characterized by
an impaired skin barrier function and abnormal immune response. Many elderly patients …

Skin is one of the indispensable organs for life. The epidermis at the outermost surface
provides a permeability barrier to infectious agents, chemicals, and excessive loss of water …

Excessive exposure to solar radiation is associated with several deleterious effects on
human skin. These effects vary from the occasional simple sunburn to conditions resulting …