Neutrophils in viral infections: current concepts and caveats

IE Galani, E Andreakos - Journal of Leucocyte Biology, 2015 - academic.oup.com
Neutrophils are the first immune cell population recruited to sites of infection, including viral
infections, and exhibit both protective and pathologic functions. In antibacterial and …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

Regulation of human macrophage M1–M2 polarization balance by hypoxia and the triggering receptor expressed on myeloid cells-1

F Raggi, S Pelassa, D Pierobon, F Penco… - Frontiers in …, 2017 - frontiersin.org
Macrophages (Mf) are a heterogeneous population of tissue-resident professional
phagocytes and a major component of the leukocyte infiltrate at sites of inflammation …

[HTML][HTML] The TREM receptor family and signal integration

J Klesney-Tait, IR Turnbull, M Colonna - Nature immunology, 2006 - nature.com
TREM proteins are a family of cell surface receptors that participate in diverse cell
processes, including inflammation, bone homeostasis, neurological development and …

Neutrophils in viral infection

V Naumenko, M Turk, CN Jenne, SJ Kim - Cell and tissue research, 2018 - Springer
Neutrophils are the first wave of recruited immune cells to sites of injury or infection and are
crucial players in controlling bacterial and fungal infections. Although the role of neutrophils …

Single-cell profiling of Ebola virus disease in vivo reveals viral and host dynamics

D Kotliar, AE Lin, J Logue, TK Hughes, NM Khoury… - Cell, 2020 - cell.com
Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to
the challenge of experimentation in high-containment and outbreak settings. Here, we used …

TREM-1 ligand expression on platelets enhances neutrophil activation

P Haselmayer, L Grosse-Hovest… - Blood, The Journal …, 2007 - ashpublications.org
The triggering receptor expressed on myeloid cells 1 (TREM-1) plays an important role in
the innate immune response related to severe infections and sepsis. Modulation of TREM-1 …

Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes

V Gomez-Pina, A Soares-Schanoski… - The Journal of …, 2007 - journals.aai.org
Triggering receptors expressed on myeloid cell (TREM) proteins are a family of cell surface
receptors that participate in diverse cellular processes such as inflammation, coagulation …

The TREM-1/DAP12 pathway

AS Tessarz, A Cerwenka - Immunology letters, 2008 - Elsevier
DNAX activation protein of 12kDa (DAP12) is an immunoreceptor tyrosine-based activation
motif (ITAM)-bearing adapter, which couples to multiple receptors expressed on natural killer …

Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide

K Dower, DK Ellis, K Saraf, SA Jelinsky… - The Journal of …, 2008 - journals.aai.org
TREM-1 (triggering receptor expressed on myeloid cells-1) is an orphan immunoreceptor
expressed on monocytes, macrophages, and neutrophils. TREM-1 associates with and …