Sex and the development of Alzheimer's disease

CJ Pike - Journal of neuroscience research, 2017 - Wiley Online Library
Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …

Why are autism spectrum conditions more prevalent in males?

S Baron-Cohen, MV Lombardo, B Auyeung… - PLoS …, 2011 - journals.plos.org
Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer
clues to the etiology of this condition. Although the cause of this bias remains a mystery, we …

[HTML][HTML] Role of estrogen and other sex hormones in brain aging. Neuroprotection and DNA repair

S Zárate, T Stevnsner, R Gredilla - Frontiers in aging neuroscience, 2017 - frontiersin.org
Aging is an inevitable biological process characterized by a progressive decline in
physiological function and increased susceptibility to disease. The detrimental effects of …

Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring

KE Stephan, KJ Friston, CD Frith - Schizophrenia bulletin, 2009 - academic.oup.com
Over the last 2 decades, a large number of neurophysiological and neuroimaging studies of
patients with schizophrenia have furnished in vivo evidence for dysconnectivity, ie, abnormal …

Protective actions of sex steroid hormones in Alzheimer's disease

CJ Pike, JC Carroll, ER Rosario, AM Barron - Frontiers in …, 2009 - Elsevier
Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid
hormones in both women and men. In post-menopausal women, the precipitous depletion of …

Sex differences and the impact of steroid hormones on the developing human brain

S Neufang, K Specht, M Hausmann… - Cerebral …, 2009 - academic.oup.com
Little is known about the hormonal effects of puberty on the anatomy of the developing
human brain. In a voxel-based morphometry study, sex-related differences in gray matter …

[HTML][HTML] Reversal of idiopathic hypogonadotropic hypogonadism

T Raivio, J Falardeau, A Dwyer… - … England Journal of …, 2007 - Mass Medical Soc
Background Idiopathic hypogonadotropic hypogonadism, which may be associated with
anosmia (the Kallmann syndrome) or with a normal sense of smell, is a treatable form of …

Cognitive effects of hormone therapy in men with prostate cancer: a review

CJ Nelson, JS Lee, MC Gamboa, AJ Roth - Cancer, 2008 - Wiley Online Library
BACKGROUND. Men who receive androgen‐deprivation therapy (ADT) for prostate cancer
experience several side effects from this treatment. A few recent studies have examined the …

Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines

T Sarachana, R Zhou, G Chen, HK Manji, VW Hu - Genome medicine, 2010 - Springer
Background Autism spectrum disorders (ASD) are neurodevelopmental disorders
characterized by abnormalities in reciprocal social interactions and language development …

Aromatase in the brain: not just for reproduction anymore

LM Garcia‐Segura - Journal of neuroendocrinology, 2008 - Wiley Online Library
Aromatase, the enzyme that synthesises oestrogens from androgen precursors, is
expressed in the brain, where it has been classically associated with the regulation of …