The aging of the world's population has intensified interest in understanding the aging
process and devising strategies and interventions to prolong a healthy life span. Cellular …

Aging is the result of a gradual functional decline at the cellular, and ultimately, organismal
level, resulting in an increased risk of developing a variety of chronic illnesses, such as …

Senescence of vascular smooth muscle cells (VSMCs) contributes to aging-related
cardiovascular diseases by promoting arterial remodelling and stiffness. Ferroptosis is a …

Cellular senescence plays critical roles in aging, regeneration, and disease; yet, the ability
to discern its contributions across various cell types to these biological processes remains …

The skin epidermis is continually influenced by a myriad of internal and external elements.
At its basal layer reside epidermal stem cells, which fuels epidermal renovation and hair …

Melanocytic nevi (skin moles) have been regarded as a valuable example of cell
senescence occurring in vivo. However, a study of induced nevi in a mouse model reported …

Both alopecia areata (AA) and vitiligo share common pathogenesis involving, interferon‐γ
(IFN‐γ) and interleukin‐15 (IL‐15) signalling pathways that activate cytotoxic CD8+ T …

Acne keloidalis is a primary scarring alopecia characterized by longstanding inflammation in
the scalp causing keloid-like scar formation and hair loss. Histologically, acne keloidalis is …

Pain, detected by nociceptors, is an integral part of injury, yet whether and how it can impact
tissue physiology and recovery remain understudied. Here, we applied chemogenetics in …

Cellular senescence is the state in which cells undergo irreversible cell cycle arrest and
acquire diverse phenotypes. It has been linked to chronic inflammation and fibrosis in …