Oxidative DNA damage is a major cause of cell death and mutagenesis in all aerobic
organisms, and several new oxidative base lesions have been identified in recent years …

The ability to recognize and repair abnormal DNA structures is common to all forms of life.
Studies in a variety of species have identified an incredible diversity of DNA repair …

DNA is subjected to many endogenous and exogenous damages. All organisms have
developed a complex network of DNA repair mechanisms. A variety of different DNA repair …

Until recently, the Fpg family was the only major group of DNA glycosylases for which no
structural data existed. Prototypical members of this family, found in eukaryotes as well as …

The MutM [formamidopyrimidine DNA glycosylase (Fpg)] protein is a trifunctional DNA base
excision repair enzyme that removes a wide range of oxidatively damaged bases (N …

Thermo (or hyperthermo) philic microorganisms are ubiquitous having a wide range of
habitats from freshly fallen snow to pasteurized milk to geothermal areas like hot springs …

Muscodor albus belongs to a genus of endophytic fungi that inhibit and kill other fungi,
bacteria, and insects through production of a complex mixture of volatile organic compounds …

Uracil-DNA glycosylase (UDG) removes uracil generated by the deamination of cytosine or
misincorporation of deoxyuridine monophosphate. Within the UDG superfamily, a fifth UDG …

The GO system is part of the DNA base excision repair pathway and is required for the error-
free repair of 8-oxoguanine (oxoG), one of the most common oxidative DNA lesions. Due to …

An endonuclease IV homolog was identified as the product of a conceptual open reading
frame in the genome of the hyperthermophilic bacterium Thermotoga maritima. The T …