New technologies for imaging molecules, particularly optical technologies, are increasingly
being used to understand the complexity, diversity and in vivo behaviour of cancers.'Omic' …

Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

The use of immuno-PET, the combination of PET with monoclonal antibodies (mAbs), is an
attractive option to improve tumor detection and mAb quantification. The long-lived positron …

The deep tissue propagation of near-infrared (NIR) light between 700–900 nm offers new
opportunities for diagnostic imaging when employing sensitive detection techniques and …

Photodynamic therapy (PDT) is a promising approach for the treatment of superficially
localized tumors. A limitation, however, is the lack of selectivity of the photosensitizers, which …

A nonlinear, Bayesian optimization scheme is presented for reconstructing fluorescent yield
and lifetime, the absorption coefficient, and the diffusion coefficient in turbid media, such as …

Advances in the biomedical sciences have been accelerated by the introduction of many
new imaging technologies in recent years. With animal models widely used in the basic and …

Although mainly developed for preclinical research and therapeutic use, antibodies have
high antigen specificity, which can be used as a courier to selectively deliver a diagnostic …

5, 10, 15, 20-Tetrakis (3-hydroxyphenyl) chlorin (mTHPC, Temoporfin) is a widely
investigated second generation photosensitizer. Its initial use in solution form (Foscan®) is …

Purpose Fluorescence-guided surgery (FGS) provides surgeons with new opportunities to
improve real-time cancer nodule detection and tumor margin visualization. Currently, the …