Mechanism of drug resistance in bacteria: efflux pump modulation for designing of new antibiotic enhancers

H Mohanty, S Pachpute, RP Yadav - Folia Microbiologica, 2021 - Springer
Drug resistance has now become a serious concern in the domain of microbial infection.
Bacteria are becoming smarter by displaying a variety of mechanisms during drug …

Innovative approaches to treat Staphylococcus aureus biofilm-related infections

K Richter, F Van den Driessche… - Essays in …, 2017 - portlandpress.com
Many bacterial infections in humans and animals are caused by bacteria residing in biofilms,
complex communities of attached organisms embedded in an extracellular matrix. One of …

Artonin I inhibits multidrug resistance in Staphylococcus aureus and potentiates the action of inactive antibiotics in vitro

S Farooq, AT Wahab, CDA Fozing… - Journal of applied …, 2014 - academic.oup.com
Aims The emergence of multidrug‐resistant (MDR) Staphylococcus aureus is a challenge for
the treatment of infections. We report here the antimicrobial activity of artonin I against MDR …

Screening a repurposing library for potentiators of antibiotics against Staphylococcus aureus biofilms

F Van den Driessche, G Brackman… - International journal of …, 2017 - Elsevier
Staphylococcus aureus biofilms are involved in a wide range of infections that are extremely
difficult to treat with conventional antibiotic therapy. We aimed to identify potentiators of …

Non-genetic mechanisms communicating antibiotic resistance: rethinking strategies for antimicrobial drug design

OM El-Halfawy, MA Valvano - Expert opinion on drug discovery, 2012 - Taylor & Francis
Introduction: Infections by multidrug-resistant bacteria are of great concern worldwide. In
many cases, resistance is not due to the presence of specific antibiotic-modifying enzymes …

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development

J Kuratli, CA Leonard… - Journal of medical …, 2023 - microbiologyresearch.org
Introduction. Azelastine hydrochloride, a second-generation histamine H1 receptor (H1R)
antagonist, exhibits anti-chlamydial effects against Chlamydia trachomatis (CT) in HeLa …

Maraviroc, celastrol and azelastine alter Chlamydia trachomatis development in HeLa cells

J Kuratli, CA Leonard, L Nufer… - Journal of medical …, 2020 - microbiologyresearch.org
Introduction. Chlamydia trachomatis (Ct) is an obligate intracellular bacterium, causing a
range of diseases in humans. Interactions between chlamydiae and antibiotics have been …

Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia

SA Loutet, OM El-Halfawy, AN Jassem… - International journal of …, 2015 - Elsevier
Burkholderia cenocepacia and other members of the Burkholderia cepacia complex (BCC)
are highly multidrug-resistant bacteria that cause severe pulmonary infections in patients …

[PDF][PDF] Studies on anti microbial potential of non-antibiotics on resistant bacteria-A Review

K Akilandeswari, K Ruckmani - Journal of Young Pharmacists, 2015 - jyoungpharm.org
The non-chemotherapeutic compounds, synthetic compounds and naturally isolated
compounds possess good antimicrobial activity against microbial infections is a well-known …

[PDF][PDF] Anti-chlamydial treatment strategies and drug interactions

J Kuratli - 2022 - zora.uzh.ch
Chlamydia trachomatis (CT) is a well-known Gram-negative bacterial pathogen with a
distinct bi-phasic lifecycle. Ocular CT strains cause trachoma while genital CT strains lead to …