Modern management of relapsed and refractory aggressive B-cell lymphoma: a perspective on the current treatment landscape and patient selection for CAR T-cell …

V Bachanova, MA Perales, JS Abramson - Blood Reviews, 2020 - Elsevier
Approximately 65% of patients with diffuse large B-cell lymphoma are cured with first-line
therapy. However, approximately 10% to 15% exhibit primary refractory disease, and 20% to …

Primary mediastinal B-cell lymphoma: a 2021 update on genetics, diagnosis, and novel therapeutics

Z Ahmed, SS Afridi, Z Shahid, Z Zamani… - … Myeloma and Leukemia, 2021 - Elsevier
Primary mediastinal large B-cell lymphoma (PMBCL) is an aggressive B-cell lymphoma
arising from thymic B-cells having clinicopathologic features distinct from systemic diffuse …

R‐CHOP versus dose‐adjusted R‐EPOCH in frontline management of primary mediastinal B‐cell lymphoma: a multi‐centre analysis

NN Shah, A Szabo, SF Huntington… - British journal of …, 2018 - Wiley Online Library
Primary mediastinal (thymic) large B‐cell lymphoma (PMBCL) is an uncommon subtype of
non‐Hodgkin lymphoma (NHL) that presents with a mediastinal mass and has unique …

Advances in diagnosis and management of diffuse large B-cell lymphoma

F Cabanillas, B Shah - Clinical Lymphoma Myeloma and Leukemia, 2017 - Elsevier
The management of diffuse large B-cell lymphoma (DLBCL) has been gradually evolving
since the discovery of its 2 major forms, the germinal center B-like (GCB) and activated B …

Primary mediastinal large B-cell lymphoma

VR Bhatt, R Mourya, R Shrestha, JO Armitage - Cancer Treatment Reviews, 2015 - Elsevier
The management of primary mediastinal large B-cell lymphoma (PMBCL) requires a
balance between optimizing chances of cure and reducing risk of long-term toxicities. The …

Meta-analysis of MS-based proteomics studies indicates interferon regulatory factor 4 and nucleobindin1 as potential prognostic and drug resistance biomarkers in …

M Ejtehadifar, S Zahedi, P Gameiro, J Cabeçadas… - Cells, 2023 - mdpi.com
Simple Summary Mass spectrometry-based proteomics studies have suggested various
proteins as diagnostic, prognostic, and druggable targets in diffuse large B cell lymphoma …

Ruxolitinib shows activity against Hodgkin lymphoma but not primary mediastinal large B-cell lymphoma

SJ Kim, DH Yoon, HJ Kang, JY Hong, HS Lee, SY Oh… - BMC cancer, 2019 - Springer
Background The upregulated expression of the JAK/STAT pathway promotes tumor growth
in Hodgkin lymphoma (HL) and primary mediastinal large B-cell lymphoma (PMBCL). Based …

Economic burden following allogeneic hematopoietic stem cell transplant in patients with diffuse large B-cell lymphoma

RT Maziarz, Y Hao, A Guerin, G Gauthier… - Leukemia & …, 2018 - Taylor & Francis
This study describes short-term and long-term healthcare resource utilization (HRU) and
costs following an allogeneic hematopoietic stem cell transplant (HSCT) in adult patients …

Primary mediastinal large B-cell lymphoma: a review for radiologists

D Pfau, DA Smith, R Beck, KA Gilani… - American Journal of …, 2019 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this article is to provide a primer for radiologists focused on
integrating the radiologic, pathologic, and clinical features of primary mediastinal large B …

Favorable outcome of primary mediastinal large B-cell lymphoma patients treated with sequential RCHOP-RICE regimen without radiotherapy

N Goldschmidt, G Kleinstern, M Orevi, O Paltiel… - Cancer chemotherapy …, 2016 - Springer
Purpose Outcomes in primary mediastinal B cell lymphoma (PMBL) improved with the
introduction of dose intense treatments, consolidation radiotherapy and rituximab. DA …