The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

Anorexia nervosa is a psychiatric disorder characterized by altered body image, persistent
food restriction and low body weight, and is associated with global endocrine dysregulation …

Abstract GH and IGF-I are important regulators of bone homeostasis and are central to the
achievement of normal longitudinal bone growth and bone mass. Although GH may act …

A large body of literature documents the occurrence of alterations in the physiology of both
central and peripheral modulators of appetite in acute patients with anorexia nervosa (AN) …

Anorexia nervosa (AN) is a serious and often fatal illness. Despite decades of research,
investigators have failed to adequately advance our understanding of the biological aspects …

abstract Context: The endocrinopathies associated with eating disorders involve multiple
systems and mechanisms designed to preserve energy and protect essential organs. Those …

States of under-nutrition are characterized by growth hormone resistance. Decreased total
energy intake, as well as isolated protein-calorie malnutrition and isolated nutrient …

Anorexia nervosa is a syndrome, that is collections of symptoms, which is not defined by its
etiology. The severe cases are intractable. The syndrome is associated with multiple …

Famine and starvation have punctuated the evolutionary past of the human species. As
such, we have developed hormonal responses to undernutrition that minimize energy …

Context: Anorexia nervosa is a primary psychiatric disorder with serious endocrine
consequences, including dysregulation of the gonadal, adrenal, and GH axes, and severe …