Multiphysics and multiscale modelling, data–model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics
R Chabiniok, VY Wang… - Interface …, 2016 - royalsocietypublishing.org
With heart and cardiovascular diseases continually challenging healthcare systems
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …
A guide for assessment of myocardial stiffness in health and disease
JC Villalobos Lizardi, J Baranger, MB Nguyen… - Nature Cardiovascular …, 2022 - nature.com
Myocardial stiffness is an intrinsic property of the myocardium that influences both diastolic
and systolic cardiac function. Myocardial stiffness represents the resistance of this tissue to …
and systolic cardiac function. Myocardial stiffness represents the resistance of this tissue to …
Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …
various cardiac diseases, which remain the most common cause of death in the developed …
The importance of the pericardium for cardiac biomechanics: from physiology to computational modeling
MR Pfaller, JM Hörmann, M Weigl, A Nagler… - … and modeling in …, 2019 - Springer
The human heart is enclosed in the pericardial cavity. The pericardium consists of a layered
thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in …
thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in …
A monolithic 3D‐0D coupled closed‐loop model of the heart and the vascular system: experiment‐based parameter estimation for patient‐specific cardiac mechanics
M Hirschvogel, M Bassilious… - … journal for numerical …, 2017 - Wiley Online Library
A model for patient‐specific cardiac mechanics simulation is introduced, incorporating a 3‐
dimensional finite element model of the ventricular part of the heart, which is coupled to a …
dimensional finite element model of the ventricular part of the heart, which is coupled to a …
Studying dynamic myofiber aggregate reorientation in dilated cardiomyopathy using in vivo magnetic resonance diffusion tensor imaging
C Von Deuster, E Sammut, L Asner… - Circulation …, 2016 - Am Heart Assoc
Background—The objective of this study is to assess the dynamic alterations of myocardial
microstructure and strain between diastole and systole in patients with dilated …
microstructure and strain between diastole and systole in patients with dilated …
[HTML][HTML] Robust and efficient fixed-point algorithm for the inverse elastostatic problem to identify myocardial passive material parameters and the unloaded reference …
Image-based computational models of the heart represent a powerful tool to shed new light
on the mechanisms underlying physiological and pathological conditions in cardiac function …
on the mechanisms underlying physiological and pathological conditions in cardiac function …
An integrated workflow for building digital twins of cardiac electromechanics—A multi-fidelity approach for personalising active mechanics
Personalised computer models of cardiac function, referred to as cardiac digital twins, are
envisioned to play an important role in clinical precision therapies of cardiovascular …
envisioned to play an important role in clinical precision therapies of cardiovascular …
Quantitative characterization of viscoelastic behavior in tissue-mimicking phantoms and ex vivo animal tissues
Viscoelasticity of soft tissue is often related to pathology, and therefore, has become an
important diagnostic indicator in the clinical assessment of suspect tissue. Surgeons …
important diagnostic indicator in the clinical assessment of suspect tissue. Surgeons …
Changes and classification in myocardial contractile function in the left ventricle following acute myocardial infarction
In this research, we hypothesized that novel biomechanical parameters are discriminative in
patients following acute ST-segment elevation myocardial infarction (STEMI). To identify …
patients following acute ST-segment elevation myocardial infarction (STEMI). To identify …