In this article, we review an important cytogenetic technique-fluorescence in situ
hybridization (FISH)-which is used for obtaining spatial genomic and transcriptomic …

The ability to perturb individual cells and to obtain information at the single-cell level is of
central importance for addressing numerous biological questions. Atomic force microscopy …

Fluidic force microscopy (FluidFM), which combines atomic force microscopy (AFM) with
microchanneled cantilevers connected to a pressure controller, is a technique allowing the …

Hydrodynamic phenomena are ubiquitous in living organisms and can be used to
manipulate cells or emulate physiological microenvironments experienced in vivo …

The investigation of human disease mechanisms is difficult due to the heterogeneity in gene
expression and the physiological state of cells in a given population. In comparison to bulk …

Single-cell analysis has been considered as a promising way to uncover the underlying
mechanisms guiding the mysteries of life activities, which considerably complements …

High-efficiency zebrafish (embryo) handling platforms are crucially needed to facilitate the
deciphering of the increasingly expanding vertebrate–organism model values. However, the …

The fundamental mechanisms of complex neural computation remain largely unknown,
especially in respect to the characteristics of distinct neural circuits within the mammalian …

Upon contact with bodily fluids, synthetic materials spontaneously acquire a layer of various
species (most notably proteins) on their surface. The concern with respect to biomedical …

This review describes the potential of FluidFM technology and its implementation in studying
the interface between a single cell (prokaryote or eukaryote) and a surface or a surrounding …