EGR1 knockdown confers protection against ferroptosis and ameliorates intervertebral disc cartilage degeneration by inactivating the MAP3K14/NF-κB axis
J Zhang, L He, Q Li, J Gao, E Zhang, H Feng - Genomics, 2023 - Elsevier
This study explored whether EGR1-MAP3K14-NF-κB axis regulated ferroptosis and IVD
cartilage generation. EGR1 and MAP3K14 expression levels were determined in CEP …
cartilage generation. EGR1 and MAP3K14 expression levels were determined in CEP …
ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus
Background Recently, we demonstrated that estrogen (E 2) induces early growth response 1
(Egr1) to mediate its actions on the uterine epithelium by controlling progesterone receptor …
(Egr1) to mediate its actions on the uterine epithelium by controlling progesterone receptor …
Estrogen induces EGR1 to fine‐tune its actions on uterine epithelium by controlling PR signaling for successful embryo implantation
HR Kim, YS Kim, JA Yoon, SC Yang, M Park… - The FASEB …, 2018 - Wiley Online Library
The harmonized actions of ovarian E2 and progesterone (P4) regulate the proliferation and
differentiation of uterine cells in a spatiotemporal manner. Imbalances between these …
differentiation of uterine cells in a spatiotemporal manner. Imbalances between these …
Estrogen-induced transcription factor EGR1 regulates c-Kit transcription in the mouse uterus to maintain uterine receptivity for embryo implantation
M Park, HR Kim, YS Kim, SC Yang, JA Yoon… - Molecular and Cellular …, 2018 - Elsevier
Abstract Early growth response 1 (Egr1) is a key transcription factor that mediates the action
of estrogen (E 2) to establish uterine receptivity for embryo implantation. However, few direct …
of estrogen (E 2) to establish uterine receptivity for embryo implantation. However, few direct …
FRZB is regulated by the transcription factor EGR1 and inhibits the growth and invasion of triple-negative breast cancer cells by regulating the JAK/STAT3 pathway
H Liu, Y Mei, X Ma, X Zhang, W Nie - Clinical breast cancer, 2022 - Elsevier
Background To explore the expression of frizzled related protein (FRZB) in triple-negative
breast cancer (TNBC) and role of FRZB in TNBC cell growth and invasion. Methods Breast …
breast cancer (TNBC) and role of FRZB in TNBC cell growth and invasion. Methods Breast …
[HTML][HTML] Regulation of cyclic AMP-response element binding protein zhangfei (CREBZF) expression by estrogen in mouse uterus
H Jang - Development & Reproduction, 2018 - ncbi.nlm.nih.gov
ABSTRACT CREBZF (cAMP-response element binding protein zhangfei) is a member of
ATF/CREB family, and which regulates various cellular functions by suppressing major …
ATF/CREB family, and which regulates various cellular functions by suppressing major …
Oestrogen-induced expression of decay accelerating factor is spatiotemporally antagonised by progesterone–progesterone receptor signalling in mouse uterus
M Lee, HA Lee, M Park, HK Park, YS Kim… - Reproduction …, 2018 - CSIRO Publishing
Decay accelerating factor (DAF) is upregulated in the fetoplacental trophoblast, which
protects the fetus from maternal complement injury. DAF was found to be downregulated in …
protects the fetus from maternal complement injury. DAF was found to be downregulated in …