Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Sialic acids (Sia) are involved in many biological activities and frequently exist as monosialyl
residues at the non-reducing terminal end of glycoconjugates. Occasionally, polymerized …

Sialic acids are a family of 9-carbon monosaccharides with particular physicochemical
properties. They modulate the biological functions of the molecules that carry them and are …

The sialic acid (Sia) N-acetylneuraminic acid (Neu5Ac) and its hydroxylated derivative N-
glycolylneuraminic acid (Neu5Gc) differ by one oxygen atom. CMP-Neu5Gc is synthesized …

Eosinophil accumulation is a characteristic feature of the immune response to parasitic
worms and allergens. The cell surface carbohydrate-binding receptor Siglec-F is highly …

Abstract The hazardous substance Neu5Gc (N-glycolylneuraminic acid), which is rich in red
meat, is related to chronic inflammation but is hard to eliminate. Here, electrical stimulation …

Glycosylation of proteins and lipids occurs in vertebrates, usually terminating with sialylation,
which regulates the physicochemical and biological properties of these glycoconjugates …

In a comparison of sialidase activities toward N-acetylneuraminic acid (Neu5Ac) and N-
glycolylneuraminic acid (Neu5Gc), we found that Salmonella typhimurium LT2 sialidase …

Although the structural diversity of sialic acid (Sia) is rapidly expanding, understanding of its
biological significance has lagged behind. Advanced technologies to detect and probe …

N-glycolylneuraminic acid (Neu5Gc) is an abundant sialic acid in many mammals and is
present in the glycoconjugates of most deuterostome animals. Neu5Gc also occurs in fresh …