In the last decades, the development of new technologies applied to lipidomics has
revitalized the analysis of lipid profile alterations and the understanding of the underlying …

The central nervous system (CNS) has the highest concentration of lipids in the organism
after adipose tissue. Among these lipids, the brain is particularly enriched with …

Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

The prevalence of depression has dramatically increased, and it has been estimated that
over 300 million people suffer from depression all over the world. Depression is highly …

Affective disorders including depression and anxiety are among the most prevalent
behavioral abnormalities in patients with Alzheimer's disease (AD), which affect the quality …

Recent findings suggest that soluble forms of amyloid-β (sAβ) peptide contribute to synaptic
and cognitive dysfunctions in early stages of Alzheimer's disease (AD). On the other hand …

Globally, more than 250 million people are affected by depression (major depressive
disorder; MDD), a serious and debilitating mental disorder. Currently available treatment …

Inflammation stimulates the hypothalamic-pituitary adrenal (HPA) axis and triggers glial
neuroinflammatory phenotypes, which reduces monoamine neurotransmitters by activating …

Abstract Alzheimer's disease (AD), the commonest progressive neurodegenerative disorder
of the brain, is clinically characterized by the formation of extracellular amyloid plaques and …

Chronic stress is considered a widely accepted risk factor for the development of
neuropsychiatric and neurological disorders. Indeed, high cortisol levels, and, thus …