Challenges and recent progress in oral drug delivery systems for biopharmaceuticals

B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Stimulus-responsive sequential release systems for drug and gene delivery

S Ahmadi, N Rabiee, M Bagherzadeh, F Elmi, Y Fatahi… - Nano today, 2020 - Elsevier
In recent years, a range of studies have been conducted with the aim to design and
characterize delivery systems that are able to release multiple therapeutic agents in …

Development of thermo/pH-responsive chitosan coated pectin-graft-poly (N, N-diethyl acrylamide) microcarriers

N Işıklan, Ş Tokmak - Carbohydrate polymers, 2019 - Elsevier
Pectin based micro/nanocarriers display promising properties for biomedical applications. In
this study, thermo/pH-responsive chitosan coated pectin-graft-poly (N, N-diethyl …

Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core–shell like microstructures for pH switchable on-demand anti-cancer drug delivery

S Chibh, V Katoch, A Kour, F Khanam, AS Yadav… - Biomaterials …, 2021 - pubs.rsc.org
Asymmetric nanostructures such as nanobowls (NBs) can exhibit superior drug delivery
performances owing to their concave structure and interior asymmetric cavities. Here, we …

Customized hybrid and NIR-light triggered thermoresponsive drug delivery microparticles synthetized by photopolymerization in a one-step flow focusing continuous …

IO de Solorzano, G Mendoza, M Arruebo… - Colloids and Surfaces B …, 2020 - Elsevier
Photopolymerization is a selective technique that takes advantage of light-sensitive
molecules to initiate and propagate monomeric structures to render covalently bonded …

PH responsive polymers in drug delivery

MF Mutalabisin, B Chatterjee… - Research Journal of …, 2018 - indianjournals.com
Stimuli-responsive polymer or 'intelligent'polymer recently emerged as new potential for
drug delivery. Some stimuli have been listed such as thermo, light, ultrasound and pH. In this …

Halloysite nanotube-embedded microparticles for intestine-targeted co-delivery of biopharmaceuticals

B Homayun, HJ Choi - International Journal of Pharmaceutics, 2020 - Elsevier
Microparticles (MPs) with pH-responding macropores have recently proved their
significance for the delivery of vulnerable biomolecules for oral drug administration. The …

Macropored microparticles with a core–shell architecture for oral delivery of biopharmaceuticals

B Homayun, A Kumar, PTH Nascimento… - Archives of pharmacal …, 2018 - Springer
Microparticles (MPs) have been extensively researched as a potential drug delivery vehicle.
Here, we investigated the fabrication of MPs with pH-responsive macropores and evaluated …

电沉积法制备丝素蛋白基水凝胶及其释药性能研究.

方昊, 罗珏君, 李梦妍, 李佩珊, 张小宁 - Journal of Silk, 2023 - search.ebscohost.com
为开发一种无毒无污染且缓释时间长的丝素蛋白(SF) 基药物缓释载体, 本文采用电沉积法在低
电压下制备SF 基水凝胶, 分析了不同制备电压, 溶液中不同SF 质量比下制得水凝胶的宏观形貌 …

Preparation of Ultrasmall Gold Nanoparticles for Nuclear-Based Gene Delivery

Z Liao, S Huo, XJ Liang - Gene Delivery, 2022 - Springer
The construction of safe and efficient gene delivery vectors is still facing challenges during
effective gene therapy. We previously reported a nuclear-based gene delivery strategy in …