Euglenozoa: taxonomy, diversity and ecology, symbioses and viruses
Euglenozoa is a species-rich group of protists, which have extremely diverse lifestyles and a
range of features that distinguish them from other eukaryotes. They are composed of free …
range of features that distinguish them from other eukaryotes. They are composed of free …
Alternative splicing: a pivotal step between eukaryotic transcription and translation
Alternative splicing was discovered simultaneously with splicing over three decades ago.
Since then, an enormous body of evidence has demonstrated the prevalence of alternative …
Since then, an enormous body of evidence has demonstrated the prevalence of alternative …
Regulation of alternative splicing through coupling with transcription and chromatin structure
Alternative precursor messenger RNA (pre-mRNA) splicing plays a pivotal role in the flow of
genetic information from DNA to proteins by expanding the coding capacity of genomes …
genetic information from DNA to proteins by expanding the coding capacity of genomes …
The Genome of the Kinetoplastid Parasite, Leishmania major
AC Ivens, CS Peacock, EA Worthey, L Murphy… - Science, 2005 - science.org
Leishmania species cause a spectrum of human diseases in tropical and subtropical
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …
Acidocalcisomes? Conserved from bacteria to man
Recent work has shown that acidocalcisomes, which are electron-dense acidic organelles
rich in calcium and polyphosphate, are the only organelles that have been conserved during …
rich in calcium and polyphosphate, are the only organelles that have been conserved during …
Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution
Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei
Unusually for a eukaryote, genes transcribed by RNA polymerase II (pol II) in Trypanosoma
brucei are arranged in polycistronic transcription units. With one exception, no pol II …
brucei are arranged in polycistronic transcription units. With one exception, no pol II …
Post-transcriptional regulation of gene expression in trypanosomes and leishmanias
Gene expression in Kinetoplastids is very unusual in that the open reading frames are
arranged in long polycistronic arrays, monocistronic mRNAs being created by post …
arranged in long polycistronic arrays, monocistronic mRNAs being created by post …
The Transcriptome of the Human Pathogen Trypanosoma brucei at Single-Nucleotide Resolution
NG Kolev, JB Franklin, S Carmi, H Shi… - PLoS …, 2010 - journals.plos.org
The genome of Trypanosoma brucei, the causative agent of African trypanosomiasis, was
published five years ago, yet identification of all genes and their transcripts remains to be …
published five years ago, yet identification of all genes and their transcripts remains to be …
Trans-Splicing in Trypanosomes: Machinery and Its Impact on the Parasite Transcriptome
S Michaeli - Future microbiology, 2011 - Taylor & Francis
In trypanosomes, all RNAs are processed by the concerted action of trans-splicing and
polyadenylation. In trans-splicing, a common spliced leader (SL) is donated to all mRNAs …
polyadenylation. In trans-splicing, a common spliced leader (SL) is donated to all mRNAs …