Since the discovery of SUMO twenty years ago, SUMO conjugation has become a widely
recognized post-translational modification that targets a myriad of proteins in many …

Protein conjugation with Small ubiquitin-like modifier (SUMOylation) has critical roles during
cell cycle progression. Many important cell cycle regulators, including many oncogenes and …

Cellular bodies such as P bodies and PML nuclear bodies (PML NBs) appear to be phase-
separated liquids organized by multivalent interactions among proteins and RNA molecules …

The post-translational modification SUMOylation is a major regulator of protein function that
plays an important role in a wide range of cellular processes. SUMOylation involves the …

SUMOylation, as a post-translational modification, plays essential roles in various biological
functions including cell growth, migration, cellular responses to stress and tumorigenesis …

The promyelocytic leukaemia (PML) tumour suppressor protein epitomizes the PML-nuclear
body (PML-NB) and is crucially required for the proper assembly of this macromolecular …

The eukaryotic ubiquitin family encompasses nearly 20 proteins that are involved in the
posttranslational modification of various macromolecules. The ubiquitin-like proteins (UBLs) …

Drug transporter proteins are critical to the distribution of a wide range of endogenous
compounds and xenobiotics such as hormones, bile acids, peptides, lipids, sugars, and …

SUMOs (small ubiquitin-like modifiers) are ubiquitin-related proteins that become covalently
conjugated to cellular target proteins that are involved in a variety of processes. Frequently …

SUMO (small ubiquitin-like modifier) modification regulates many cellular processes,
including transcription. Although sumoylation often occurs on specific lysines within the …